Results 111 to 120 of about 20,264,016 (337)

On the Integrability of Quasihomogeneous Systems and Quasidegenerate Infinity Systems

open access: yesAdvances in Difference Equations, 2007
The integrability of quasihomogeneous systems is considered, and the properties of the first integrals and the inverse integrating factors of such systems are shown.
Hu Yanxia
doaj   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Integration of fertility management, cultivar selection and alternative spray treatments to optimize control of foliar diseases of greenhouse grown tomatoes [PDF]

open access: yes, 2007
Powdery mildew caused by Leveillula taurica (Lev.) Arn. is one of the most serious foliar diseases of greenhouse and open field tomato. The disease is currently controlled with the use of organic fungicides and sulphur, the latter being the only product ...
Dafermos, N.G.   +3 more
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Multilevel (ML-ICLV) & Single Level Integrated Discrete Choice and Latent Variable (ICLV) Models Using Alternative Latent Structures' Conceptualizations [PDF]

open access: yes, 1951
The aim of the present endeavor is to experiment on integrating discrete choice with latent variable (ICVL) models using alternative factorial structures’ conceptualizations and do so at both Single Level (Level 0) and Multilevel (ML-ICVL).
Chrysochoidis, Georgios, Wilson, Charlie
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Ambiance Factors, Emotions, and Web User Behaviour:a Model Integrating and Affective and Symbolical Approach [PDF]

open access: yes
The present paper addresses the efficiency of manipulating music in a merchant website, and it:- proposes a review of the literature on ambiance factors in advertising & shopping behaviour, capitalizing on it to:- propose a theoretical framework that ...
Lambert, Brice
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Integrating regional transportation and ecological factors into anaerobic digestion siting decisions

open access: yesnpj Sustainable Agriculture
Landfilling wasted food (WF) is a significant source of greenhouse gas emissions. Anaerobic digestion (AD) is emerging as a promising alternative to jointly manage WF and generate bio-based energy, yet its widespread adoption is limited by transportation
William R. Armington   +4 more
doaj   +1 more source

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