Results 91 to 100 of about 1,713,861 (267)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Reliable Assessment of Healthcare Procedures: A Comparison of On-Site and Video-Based Methods
Advances in Medical Education and PracticeMinghui Yi,1 Yao Zhang,2 Fei Wu,1 Shilong Zhang,3 Menghui Hu,1 Changmei Liu,1 Bin Zheng,2 Jinling Yang1 1Medical Integration and Practice Center, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, People’s Republic of China; 2Surgical ...
Yi M +7 more
doaj
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
A driving feel oriented dynamic model for commercial vehicles
Scientific ReportsVirtual testing and evaluation of commercial vehicles require an accurate and comprehensive dynamic model to replace traditional driver-based field testing, thereby shortening the development cycle of commercial vehicles. However, existing dynamic models
Li Li +4 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Nature CommunicationsImage-guided surgery systems require precise fusion of fluorescence mapping and structural background imaging, yet current dual-camera system methods suffer from field-of-view misalignment and pixel offsets, risking millimeter-scale surgical errors.
Yujin Liu +12 more
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Revista de Pesquisa Cuidado é Fundamental OnlineObjetivo: analisar os efeitos de uma oficina educativa sobre prevenção da violência obstétrica no conhecimento de agentes comunitários de saúde. Método: estudo quase-experimental realizado em Acarape, Ceará, Brasil, em dezembro de 2024.
Maria Eduarda Silva Barroso +4 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source