Results 111 to 120 of about 8,201,628 (359)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Electrical Effect of Nitrogen Implanted Into LDD of MOSFETs

IEEE Journal of the Electron Devices Society
The motivation of this study was to solve the high $\rm I_{D,off}$ problem in 8 Volt N-channel MOSFET. We experimented with implanting nitrogen into LDD at various doses.
Yoo Seon Song, Markus Lenski, Mohammed F. Karim, Keith Flynn, Jan Hoentschel, Carsten Peters, Jens-Uwe Sachse, Omur Isil Aydin, Jun Wu, Bastian Hausdorfer, Mahesh Siddabathula, Konrad Semmler, Jurgen Daleiden   +12 more
doaj   +1 more source

Adaptive Integration and Improper Integrals [PDF]

Mathematics of Computation, 1975
Let R be the class of all functions that are properly Riemann-integrable on [0, 1], and let IR be the class of all functions that are properly Riemann-integrable on [a, 1] for all a > 0 a > 0 and for which \[ lim a →
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Computational Methods for Single-Cell Multi-Omics Integration and Alignment [PDF]

, 2022
Stefan Stanojevic, Yijun Li, Lana X. Garmire   +2 more
openalex   +1 more source

Semantic Integration Portal

, 2007
The Semantic Integration Portal is a demonstration of the potential capabilities of Semantic Web applications in a knowledge-rich context. Source data is taken from different online terrorist incident aggregators and marked up according to ontologies ...
Braines, Dave, Hendler, James A, McRae-Spencer, Duncan, Shadbolt, Nigel R, Smart, Paul R   +4 more
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Frequency transfer and inverse design for metasurface under multi-physics coupling by Euler latent dynamic and data-analytical regularizations

Nature Communications
Frequency transfer is a key challenge in machine learning as it allows researchers to go beyond in-range analyses of spectrum properties towards out-of-the-range predictions. Traditionally, to predict properties at a specific frequency, targeted spectrum
Enze Zhu, Zheng Zong, Erji Li, Yang Lu, Jingwei Zhang, Hao Xie, Ying Li, Wen-Yan Yin, Zhun Wei   +8 more
doaj   +1 more source

Monolithically Integrated Multiwavelength Laser With Optical Feedback: Damped Relaxation Oscillation Dynamics and Narrowed Linewidth

IEEE Photonics Journal, 2018
An InP-based, monolithically integrated multiwavelength laser with optical feedback is presented. We demonstrate the performance of the dual-wavelength operation. Single-mode lasing is obtained for each of the two channels within a temperature range from
Dan Zhao, Stefanos Andreou, Weiming Yao, Daan Lenstra, Kevin Williams, Xaveer Leijtens   +5 more
doaj   +1 more source

Strong convergence of projective integration schemes for singularly perturbed stochastic differential systems [PDF]

, 2006
Dror Givon, Ioannis G. Kevrekidis, Raz Kupferman   +2 more
openalex   +1 more source