Results 131 to 140 of about 8,201,628 (359)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

A driving feel oriented dynamic model for commercial vehicles

Scientific Reports
Virtual testing and evaluation of commercial vehicles require an accurate and comprehensive dynamic model to replace traditional driver-based field testing, thereby shortening the development cycle of commercial vehicles. However, existing dynamic models
Li Li, Hsin Guan, Chunguang Duan, Le Jiang, Jun Zhan   +4 more
doaj   +1 more source

Labor Market Integration between Northern Mexico and Southern United States: an empirical investigation. [PDF]

In this paper, the analysis of co-dependence between the US and Mexico labor markets is carried out by estimating the cyclical component of California’s and Texas’ manufacturing employment and four US Border Mexican cities through the Hodrick-Prescott ...
Alejandro Islas-Camargo, Willy Walter Cortez   +1 more
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Fruit-Fly optimization based feature integration in image retrieval

, 2021
Pavithra Latha Kumaresan, Subbulakshmi Pasupathi, Sindhia Lingaswamy, Sreesharmila Thangaswamy, Vimal Shunmuganathan, Danilo Pelusi   +5 more
openalex   +1 more source

Integrating with integrity [PDF]

Nature Genetics, 2010
openaire   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Introducing a New Journal: BIO Integration

BIO Integration, 2020
Zhiyi Chen, Pintong Huang
doaj   +1 more source

Effect of an educational workshop on the prevention of obstetric violence on the knowledge of community health agents / Efeito de oficina educativa sobre a prevenção da violência obstétrica no conhecimento de agentes comunitários de saúde

Revista de Pesquisa Cuidado é Fundamental Online
Objetivo: analisar os efeitos de uma oficina educativa sobre prevenção da violência obstétrica no conhecimento de agentes comunitários de saúde. Método: estudo quase-experimental realizado em Acarape, Ceará, Brasil, em dezembro de 2024.
Maria Eduarda Silva Barroso, Fernanda Nadja Rodrigues Sousa, Débora Letícia Beserra Silva, Nathanael Souza Maciel, Camila Chaves da Costa   +4 more
doaj   +1 more source