Results 121 to 130 of about 4,379,016 (366)

Institute on Community Integration Annual Report: 1995-96

open access: yes, 1996
The annual report summarizing the work and community impact of the Institute on Community Integration, a federally–designated University Affiliated Program on Developmental Disabilities working to improve community services and social supports for ...
Institute on Community Integration
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Is the EU internal market suffering from an integration deficit? Estimating the 'home-bias effect.' CEPS Working Document No. 348, May 2011 [PDF]

open access: yes, 2011
As an alternative to measuring the extent of market integration, ‘home-bias’ indicates the degree to which economic agents ‘over-prefer’ to transact with domestic agents rather than agents from other EU countries. Such an exclusive preference is measured
Pacchioli, Consuelo., Consuelo Pacchioli
core  

Introducing a New Journal: BIO Integration

open access: yesBIO Integration, 2020
Zhiyi Chen, Pintong Huang
doaj   +1 more source

A driving feel oriented dynamic model for commercial vehicles

open access: yesScientific Reports
Virtual testing and evaluation of commercial vehicles require an accurate and comprehensive dynamic model to replace traditional driver-based field testing, thereby shortening the development cycle of commercial vehicles. However, existing dynamic models
Li Li   +4 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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