Results 121 to 130 of about 2,948,600 (354)

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

The effects of forest canopy shading and turbulence on boundary layer ozone

Nature Communications, 2017
Fully quantifying the influence of vegetation on atmospheric chemistry remains challenging. Here, the authors show that forest canopy shading and turbulence significantly modify air pollution throughout the atmospheric boundary layer, and must be taken ...
P. A. Makar, R. M. Staebler, A. Akingunola, J. Zhang, C. McLinden, S. K. Kharol, B. Pabla, P. Cheung, Q. Zheng   +8 more
doaj   +1 more source

The Rise of the Xenes: From the Synthesis to the Integration Processes for Electronics and Photonics. [PDF]

Materials (Basel), 2021
Grazianetti C, Martella C.
europepmc   +1 more source

Adaptation to climate change and policy interactions in Brazil's semiarid region [Panel T14-P10 Session 2] [PDF]

, 2019
This paper analyzes the emergence of Brazil's climate adaptation agenda and discusses its divergences regarding the climate mitigation program and the missed goal of the National Adaptation Plan to promote the integration of sectoral agendas ...
Le Coq, Jean-François, Mendes, Priscylla, Milhorance, Carolina, Sabourin, Eric   +3 more
core  

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

A multiprocess quality model: identification of of key processes in the integration approach [PDF]

, 2012
In this paper we investigate the use of multiprocess quality model in the adoption of process improvement frameworks. We analyze an improvement effort based on multiple process quality models adoption.
Abd. Rahman, Aedah, Ibrahim, Suhaimi, Sahibuddin, Shamsul   +2 more
core  

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

Molecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla, Simone Venz, Ruslan Al‐Ali, Martin Wendlandt, Mandy Radefeldt, Elke Krüger   +5 more
wiley   +1 more source

Sample-Continuity of Square-Integrable Processes [PDF]

, 1977
Marjorie G. Hahn, Michael J. Klass
openalex   +1 more source

MULTILATERAL NEGOTIATIONS, REGIONAL INTEGRATION PROCESSES AND THE CAP. WHAT'S AHEAD? [PDF]

The focus of the paper is on the developments so far and the future of the negotiations on agriculture in the WTO Doha Development Agenda round from the perspective of the European Union.
Anania, Giovanni
core   +1 more source

Data-driven modelling of biological multi-scale processes

, 2015
Biological processes involve a variety of spatial and temporal scales. A holistic understanding of many biological processes therefore requires multi-scale models which capture the relevant properties on all these scales.
Hasenauer, Jan, Hross, Sabrina, Jagiella, Nick, Theis, Fabian J.   +3 more
core   +1 more source