Results 61 to 70 of about 291,654 (266)

Integrating Theories of Working Memory

, 2020
Multiple theories of working memory are described in the chapters of this book and often these theories are viewed as being mutually incompatible, yet each is associated with a supporting body of empirical evidence. This chapter argues that many of these differences reflect different research questions, different levels of explanation, and differences ...
Logie, Robert, Belletier, Clement, Doherty, Jason   +2 more
openaire   +3 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

A modular theory of multisensory integration for motor control

Frontiers in Computational Neuroscience, 2014
To control targeted movements, such as reaching to grasp an object or hammering a nail, the brain can use divers sources of sensory information, such as vision and proprioception.
Michele eTagliabue, Joseph eMcIntyre
doaj   +1 more source

A theory of divergent integrals

Applied Mathematics Letters, 2009
For improper integrals of the form \(\int_0^\infty f(t)\,dt\), the author defines modes of convergence analogous to the various methods of summability for infinite series. Corresponding to Cesàro summability, for \(\alpha>-1\), \(f\) is \((C,\alpha)\) integrable if there is a number \(a\) such that \(\lim_{T\to+\infty}\int_0^T(1-\frac{t}{T})^\alpha f(t)
openaire   +4 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Modeling the Determinants of Global Economic Uncertainty

Proceedings of the International Conference on Applied Innovations in IT
Economic uncertainty poses a significant challenge for decision-makers across the public and private sectors. While uncertainty is an inherently nebulous concept, developing consistent quantitative measures allows for rigorous analysis of its impacts ...
Olha Kovalchuk, Kateryna Berezka, Oksana Tulai, Bohdan Ferens, Ludmila Babala, Oleksandr Zapolskyi   +5 more
doaj   +1 more source

On the Theory of an Integral Equation

Advances in Applied Mathematics, 1994
The main object of the study in the paper is the following integral equation (1) \(x(t) = f(t) - \mu \int^ \infty_ 0 K(\tau) \text{sign} [x(t - \tau)] d \tau\). Here it is assumed that \(\mu \geq 0\), \(f\) is a continuous function having only isolated zeros \(t_ k\) such that \(f'(t_ k) \neq 0\) for \(k=1,2, \dots\). Moreover, the kernel function \(K\)
openaire   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Constructive algebraic integration theory [PDF]

Annals of Pure and Applied Logic, 2006
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source