Results 51 to 60 of about 8,449,730 (256)

Introduction to the theory of integration /

open access: yes, 1971
General theory of limits -- Riemannian type of integration -- Intergrals of Riemann type of functions of intervals in two or higher dimension -- Sets -- Content and measure -- Measurable functions -- Lebesgue-Stieltjes integration -- Classes of ...
Hildebrandt, Theophil Henry
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

A modular theory of multisensory integration for motor control

open access: yesFrontiers in Computational Neuroscience, 2014
To control targeted movements, such as reaching to grasp an object or hammering a nail, the brain can use divers sources of sensory information, such as vision and proprioception.
Michele eTagliabue, Joseph eMcIntyre
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Modeling the Determinants of Global Economic Uncertainty

open access: yesProceedings of the International Conference on Applied Innovations in IT
Economic uncertainty poses a significant challenge for decision-makers across the public and private sectors. While uncertainty is an inherently nebulous concept, developing consistent quantitative measures allows for rigorous analysis of its impacts ...
Olha Kovalchuk   +5 more
doaj   +1 more source

An integration of Integrated Information Theory with fundamental physics

open access: yesFrontiers in Psychology, 2014
To truly eliminate Cartesian ghosts from the science of consciousness, we must describe consciousness as an aspect of the physical. Integrated Information Theory states that consciousness arises from intrinsic information generated by dynamical systems ...
Adam B Barrett
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Pre-measure spaces and pre-integration spaces in predicative Bishop-Cheng measure theory [PDF]

open access: yesLogical Methods in Computer Science
Bishop's measure theory (BMT) is an abstraction of the measure theory of a locally compact metric space $X$, and the use of an informal notion of a set-indexed family of complemented subsets is crucial to its predicative character.
Iosif Petrakis, Max Zeuner
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Developing Conceptualizations of Europeanization and European Integration: Mixing Methodologies [PDF]

open access: yes, 2002
In its most explicit form Europeanization is conceptualized as the process of downloading European Union (EU) directives, regulations and institutional structures to the domestic level. However, this conceptualization of Europeanization has been extended
Howell, Kerry.
core  

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