Results 41 to 50 of about 8,449,730 (256)

Die verhouding tussen integrasie- teorie en konflikteorie

Koers : Bulletin for Christian Scholarship, 1983
The author bases his article on a comparison and evaluation of the contributions of conflict theoreticians and consensus theoreticians in dealing with the phenomenon of social conflict. He looks in some detail at the development of conflict theory, and
A. D. Louw
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Metaphorical Blends (Case Study of Metaphorization of Concept BOOK)

SHS Web of Conferences, 2018
The article deals with the mechanism of creating metaphor in the context of the theory of conceptual integration. A particular emphasis is laid on the basic theses of the theory of conceptual metaphor and the theory of conceptual integration.
Berezhnykh Natalia, Sivtseva Natalia, Skopintseva Tatiana, Kontrimovich Assia   +3 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Integration between Bioinformatics Algorithms and Neutrosophic Theory

Neutrosophic Sets and Systems
This paper presents a neutrosophic inference model for bioinformatics. The model is used to develop a system for accurate comparisons of human nucleic acids, where the new nucleic acid is compared to a database of old nucleic acids.
Romany M. Farag, Mahmoud Y. Shams, Dalia A. Aldawody, Huda E. Khalid, Hazem M. El-Bakry, Ahmed A. Salama   +5 more
doaj   +1 more source

Integration of mathematical models in marketing theory and practice

Studies and Scientific Researches: Economics Edition, 2012
This article is a theoretical approach on the main mathematical models used in marketing practice. Application of general systems theory in marketing involves setting behavior assumptions as models of various processes.These models have, on the one hand,
Ioana Olariu
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

‘Integration-through-Law’: grand theory, revisionist history

European Law Open
How has the European Union been integrated in the past? Legal academics have traditionally pointed to the Court of Justice and to the broader idea of an ‘integration-through-law’.
Robert Schütze
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source