Results 101 to 110 of about 1,454,362 (289)
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
This research is based on the case of airport development in Kulonprogo Regency. The findings in this study are: First, contradictions RTRW Kulonprogo District with RTRWN, RTRW DIY Province, and RZWP3K DIY Province not in accordance with Article 7 ...
Ananda Prima Yurista
doaj +1 more source
Using a work based learning framework to deliver regeneration education for practitioners at the University of Chester [PDF]
This is the author's PDF version of an article published in Ad-Lib© 2009. The definitive version is available at www.cont-ed.cam.ac.uk/institute-media/pdfs/adlib/adlib38.pdfThis article discusses a regeneration practitioner programme delivered through ...
Talbot, Jon
core
Integrative Biological Simulation, Neuropsychology, and AI Safety
We describe a biologically-inspired research agenda with parallel tracks aimed at AI and AI safety. The bottom-up component consists of building a sequence of biophysically realistic simulations of simple organisms such as the nematode $Caenorhabditis ...
Hay, Nick J. +2 more
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Adaptive Integration and Improper Integrals [PDF]
Let R be the class of all functions that are properly Riemann-integrable on [0, 1], and let IR be the class of all functions that are properly Riemann-integrable on [a, 1] for all a > 0 a > 0 and for which \[ lim a →
openaire +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Sanjay K Agarwal,1 Warren G Foster,1,2 Erik J Groessl3,41Center for Endometriosis Research and Treatment, University of California San Diego, La Jolla, CA 92037, USA; 2Department of Obstetrics & Gynaecology, Mcmaster University, Hamilton, Ontario L8S
Agarwal SK, Foster WG, Groessl EJ
doaj
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
INTEGRATION OF PARTIALLY INTEGRABLE EQUATIONS [PDF]
12 p, WASCOM XIII (Acireale, 19-25 June 2005)
openaire +2 more sources

