Results 121 to 130 of about 3,183,342 (302)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Background: Traditional Persian Medicine (TPM) education was initiated at Shiraz University of Medical Sciences (SUMS) in 2004. Despite the critical need for evaluating the TPM education success, it remained unassessed since its implementation.
Fariba Ettehadi +3 more
doaj +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Jessica Matthews: Integrative Health Educator
Simon Matthews (Wellcoaches Australia) and Darren Morton (Avondale University) introduce the passionate people making a difference in the pioneering field of lifestyle medicine.
Matthews, Simon, Morton, Darren
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Integrative medicine for COVID-19: researches and evidence
Myeong Soo Lee, Eunhye Song
doaj +1 more source
Introducing integrative integrated migraine care (IIMC): A model and case presentation
Introduction: Chronic migraine is one of the most common neurological disorders. Although different complementary therapies are available, few are integrated into standard patient care. Concept: The Department of Integrative Medicine at the University of
Cramer, H +4 more
core +1 more source

