Results 131 to 140 of about 6,800,285 (350)

Clinical Application of the UK Working Party′s Criteria for the Diagnosis of Atopic Dermatitis in the Chinese Population by Age Group

Chinese Medical Journal, 2016
Background: Atopic dermatitis (AD) is a common inflammatory skin disease with an increasingly significant prevalence. The prevalence of AD depends greatly on how its diagnosis is done. The UK Working Party's diagnostic criteria for AD are simple and easy
Li Wang, Lin-Feng Li, on behalf of Professional Committee of Dermatology, Chinese Association of Integrative Medicine   +2 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Self-reported Improvement in Side Effects and Quality of Life With Integrative Medicine in Breast Cancer Patients

Integrative Cancer Therapies, 2018
Purpose. Although the demand from patients for integrative medicine is increasing, complementary medicine services are still quite heterogeneous and have not been incorporated into clinical routine.
Carolin C. Hack MD, Janina Hackl MD, Nina B. M. Hüttner MD, Hanna Langemann, Judith Schwitulla PhD, Svenja Dietzel-Drentwett, Peter A. Fasching MD, Matthias W. Beckmann MD, Anna-Katharin Theuser   +8 more
doaj   +1 more source

Responding to Patients' Questions About Complementary, Alternative, and Integrative Medicine

MedEdPORTAL, 2012
This resource features a collection of activities, including an independent exercise and small-group session, developed to help first- and second-year medical students explore the issues that arise when communicating with patients regarding integrative ...
Shelley Adler, Yvette Coulter, Ginger Polich, Katherine Hyland, June Chan   +4 more
doaj   +1 more source

Integration with medicine needed [PDF]

British Dental Journal, 2022
Tovani-Palone, M. R., Franchi, T.
openaire   +2 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Integrative oncology for breast cancer patients: introduction of an expert-based model

BMC Cancer, 2012
Background Malignant breast neoplasms are among the most frequent forms of cancer in the Western world. Conventional treatment of breast cancer may include surgery, hormonal therapy, chemotherapy, radiation and/or immunotherapy, all of which are often ...
Dobos Gustav J, Voiss Petra, Schwidde Ilka, Choi Kyung-Eun, Paul Anna, Kirschbaum Barbara, Saha Felix J, Kuemmel Sherko   +7 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Direct Primary Care With Implementation of Integrative Care and Impact on Patient Laboratory Markers

, 2019
This paper will discuss the impact of direct-primary care (DPC), using integrative care practices. For patients seen at Omaha Integrative Care (OIC), a retrospective chart review of the laboratory makers: Hemoglobin A1C levels, Thyroid Stimulating ...
Wieseler, Ann
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