Results 91 to 100 of about 4,692,125 (348)

Inulin‐Based Oral Chemotherapy Modulates Gut Microbiota and Immune Microenvironment through Inhibition of Neutrophil Extracellular Trap Formation for Improving Cancer Therapy

Advanced Science, EarlyView.
Schematic representation of ZIF‐8@OXA@inulin for cancer immunotherapy. Synthesis of ZIF‐8@OXA@inulin. Augmentation of pyroptosis, regulation of gut microbiota, and inhibition of NETs formation by ZIF‐8@OXA@inulin‐mediated comprehensive strategy for antitumor immune response. ABSTRACT Despite the potential of chemoimmunotherapy against colorectal cancer
Zhenhao Li, Jiaqiang Jiang, Yuping Zhou, Xinyuan Mao, Haotian Wen, Zhian Chen, Yutong Wang, Cong Huang, Yanfeng Hu   +8 more
wiley   +1 more source

Integrative taxonomy by molecular species delimitation? [PDF]

, 2017
Taxonomy aspires precise species identification and delimitation to provide basic information on biological diversity. Traditionally, taxonomy relies on comparative morphological analyses to identify species and to derive new species hypotheses. However, taxonomic capacities decreased critically in the past decades, lea ding to the so-called taxonomic ...
Kučinić, Mladen, Previšić, Ana
openaire   +2 more sources

Integrative taxonomy and the operationalization of evolutionary independence [PDF]

European Journal for Philosophy of Science, 2018
There is growing agreement among taxonomists that species are independently evolving lineages. The central notion of this conception, evolutionary independence, is commonly operationalized by taxonomists in multiple, diverging ways. This leads to a problem of operationalization-dependency in species classification, as species delimitation is not only ...
openaire   +2 more sources

Programmable Klebsiella pneumoniae Phage Tropism Enabled by Scalable Receptor‐Binding Protein Mining and Modular Assembly

Advanced Science, EarlyView.
This work introduces a scalable, data‐driven strategy that turns the vast sequence diversity of phage receptor‐binding proteins into modular tools for engineering customizable phages. By clustering and experimentally validating diverse RBPs, the authors build an accurate map linking sequence to host specificity and create plug‐and‐play modules that ...
Shisong Jing, Yiyao Song, Xianbiao Bi, Yuqin Song, Dawei Wei, Jiangqing Huang, Yuan Zeng, Gang Zhang, Rong Zhang, Chao Wang, Jie Feng   +10 more
wiley   +1 more source

Revision of the genus Eugenys Quate, 1996 (Diptera: Psychodidae), with the description of three new species

European Journal of Taxonomy
We review the diagnosis of the genus Eugenys Quate, 1996 (Diptera: Psychodidae) which occurs in the Neotropical Region. Initially known from Costa Rica, Nicaragua, and Panama, we describe one additional species from Costa Rica, Eugenys singularis sp ...
Santiago Jaume-Schinkel, Gunnar Mikalsen Kvifte   +1 more
doaj   +1 more source

How to Name and Classify Your Phage: An Informal Guide

Viruses, 2017
With this informal guide, we try to assist both new and experienced phage researchers through two important stages that follow phage discovery; that is, naming and classification.
Evelien Adriaenssens, J. Rodney Brister
doaj   +1 more source

Integrative taxonomy of an arctic bumblebee species complex highlights a new cryptic species (Apidae: Bombus)

Zoological Journal of the Linnean Society, 2019
Bumblebees have been the focus of much research, but the taxonomy of many species groups is still unclear, especially for circumpolar species. Delimiting species based on multisource datasets provides a solution to overcome current systematic issues of ...
B. Martinet, T. Lecocq, Nicolas Brasero, Maxence Gérard, K. Urbanova, I. Valterová, J. O. Gjershaug, D. Michez, P. Rasmont   +8 more
semanticscholar   +1 more source

Coalescent-based species delimitation in an integrative taxonomy

Trends in Ecology & Evolution, 2012
The statistical rigor of species delimitation has increased dramatically over the past decade. Coalescent theory provides powerful models for population genetic inference, and is now increasingly important in phylogenetics and speciation research. By applying probabilistic models, coalescent-based species delimitation provides clear and objective ...
Fujita, Matthew K., Leache, Adam D., Burbrink, Frank T., McGuire, Jimmy A, Moritz, Craig   +4 more
openaire   +3 more sources

Rapid Remodeling of the Human Gut Microbiome in Response to Short‐Term Animal Product Restriction and Associations with Host Molecular Phenotypes

Advanced Science, EarlyView.
A real‐world model of structured animal product restriction practiced for religious reasons reveals the dynamic adaptability of the human gut microbiome to dietary change and uncovers reductions in diversity and rare taxa loss. Integrated microbiome, metabolomic, and proteomic analyses uncover coordinated taxonomic and molecular shifts and identify ...
Christina Emmanouil, Maria Anezaki, Alexandros Simistiras, Stavros Glentis, Nikolaos Scarmeas, Pantelis Hatzis, Konstantinos Rouskas, Antigone S. Dimas   +7 more
wiley   +1 more source

Oral Streptococcus salivarius Couples Neutrophil IRGM1 Signaling to NET Formation and Colorectal Cancer Metastasis

Advanced Science, EarlyView.
The oral bacterium Streptococcus salivarius promotes colorectal cancer metastasis by inducing neutrophil extracellular trap (NET) formation. Mechanistically, IRGM1–IQGAP1 interaction activates Wnt5a–PI3K/AKT signaling in neutrophils, driving NET‐mediated tumor progression.
Fengyi Liu, Yuan Wang, Hengxuan Cai, Qianwen Yue, Xueli Liu, Xuanwen Bao, Zeng Wang, Xuehan Li, Lai Wei, Zhihua Zhang, Fan Xing, Yi Xu, Xianjun Li, Wei Xu   +13 more
wiley   +1 more source