Results 171 to 180 of about 227,700 (249)

Latent-TGF-β has a domain swapped architecture. [PDF]

Nat Commun
Jin M, Seed RI, Shing T, Wang L, Li J, Cheng Y, Nishimura SL.   +6 more
europepmc   +1 more source

Traction forces mediated by integrin signaling are necessary for definitive endoderm specification [PDF]

, 2015
Hermes Taylor‐Weiner, Neeraja Ravi, Adam J. Engler   +2 more
openalex   +1 more source

Multimodal Actuation and Environment Adaptive Strategies of Bio‐Inspired Micro/Nanorobots in Precision Medicine

Advanced Robotics Research, EarlyView.
An introduction for multidrive and environment‐adaptive micro/nanorobotics: design and fabrication strategies, intelligent actuation, and their applications. Various intelligent actuation approaches—magnetic, acoustic, optical, chemical, and biological—can be synergistically designed to enhance flexibility and adaptive behavior for precision medicine ...
Aiqing Ma, Han Gong, Jiacheng Ouyang, Liqi Chen, Tianfang Kang, Yiran He, Guojun Huang, Sidi Zheng, Ting Yin, Hong Pan, Lintao Cai   +10 more
wiley   +1 more source

The integrin odyssey - a journey full of fundamental discoveries. [PDF]

J Cell Sci
Fässler R, Sonnenberg A.
europepmc   +1 more source

Enhanced engraftment and immunomodulatory effects of integrin alpha-2-overexpressing mesenchymal stromal cells in lipopolysaccharide-induced acute lung injury [PDF]

Hana Kang, Ok‐Hyeon Kim, Eric L. Chang, Jin-Ho Kim, Ji-Young Kim, Geun-Seup Shin, Chul-Hong Kim, Younghyun Lim, Young‐Jin Seo, Jung-Woong Kim, Hyun Jung Lee   +10 more
openalex   +1 more source

Modulation of Cancer-Associated Fibrotic Stroma by An Integrin αvβ3 Targeting Protein for Pancreatic Cancer Treatment

, 2020
Ravi Chakra Turaga, Malvika Sharma, Falguni Mishra, Alyssa M. Krasinskas, Yi Yuan, Jenny J. Yang, Shiyuan Wang, Chun‐Feng Liu, Li Sun, Zhi‐Ren Liu   +9 more
openalex   +1 more source

CRISPR‐MI and scRNA‐Seq Reveal TREM2's Function in Monocyte Infiltration and Macrophage Apoptosis During Abdominal Aortic Aneurysm Development

Advanced Science, EarlyView.
A method is developed for conducting genome‐wide CRISPR/Cas9 screening of monocyte infiltration in vivo (CRISPR‐MI) that is easily adaptable across a variety of disease models. Through the combination of CRISPR‐MI and scRNA‐Seq, this study discovers that Trem2 is a key regulator of early monocyte infiltration in abdominal aortic aneurysm (AAA ...
Haocheng Lu, Chao Xue, Yang Zhao, Jinjian Sun, Changzhi Zhao, Xu Zhang, Guizhen Zhao, Yaozhong Liu, Hongyu Liu, Yongjie Deng, Ying Wang, Chi Zhang, Yingjie Liu, Linjun Zeng, Ying Yang, Bolun Li, Shusi Ding, Linkang Zhou, Henry Kuang, Zanxin Wang, Wenhao Ju, Haihuan Lin, Jie Lin, Yanhong Guo, Lin Chang, Hongmei Zhao, Jing Wang, Jiandie Lin, Lemin Zheng, Y. Eugene Chen, Jifeng Zhang   +30 more
wiley   +1 more source

RAD23B Promotes Colorectal Cancer Metastasis via the Talin1/Integrin/PI3K/AKT/MMP9 Axis. [PDF]

Oncol Res
Li J, Chen Y, Hao Z, Zhang Z, Fan J, Liu X, Zhao X, Zhang H, Wu C.   +8 more
europepmc   +1 more source

Integrin α8‐Mediated Pericyte Morphogenesis Controls Blood‐Brain Barrier Integrity

Advanced Science, EarlyView.
This study highlights that ITGA8 impacts pericyte morphology and function, both crucial for BBB integrity, via RhoA/ROCK signaling, thus influencing TGF‐β1 activation through cytoskeletal tension and ECM interactions. Notably, in post‐ischemic recovery models, ITGA8 deficiency exacerbates vascular dysfunction by impairing pericyte‐mediated BBB ...
Chang‐Xiong Gong, Lin‐Lin Hu, Ling Jiang, Pei‐Xia Shi, Shuang Zhang, Yuan Zhao, Bing‐Qiao Wang, Xiao‐Feng Cheng, Cheng‐Kang He, Sen Lin, Yue Dai, Zhao‐You Meng, Chen‐Hao Zhao, Bao‐Liang Sun, Qi Xie, Fang‐Fei Li, Qing‐Wu Yang   +16 more
wiley   +1 more source

Regulation of the mechanoresponsive Neat1 and PSPC1 by substrate stiffness in TGF-β1-induced renal progenitor cell fate. [PDF]

J Biomed Sci
Huang HN, Lee LW, Kuo CH, Wong TY, Chiu WT, Tang MJ.   +5 more
europepmc   +1 more source