Extracellular matrix remodeling is crucial in cancer progression. Using a peptide to probe the tension of ECM fibers, it was found that Fibronectin fibers gradually lose tension as human breast carcinoma progresses, while their tension is maintained in ductal carcinoma in situ (DCIS), the non‐invasive precursor of breast cancer. This loss of tension is
Arnaud Miéville+6 more
wiley +1 more source
Macrocyclic RGD-peptides with high selectivity for α<sub>v</sub>β<sub>3</sub> integrin in cancer imaging and therapy. [PDF]
Cheng X, Li C, Hong H, Zhou Z, Wu Z.
europepmc +1 more source
Multiple elevations of cytosolic-free Ca2+ in human neutrophils: initiation by adherence receptors of the integrin family. [PDF]
Marisa Jaconi+5 more
openalex +1 more source
Advances in Microfluidic Cochlea‐On‐A‐Chip
This review systematically examines diverse cell sources for inner ear organoids and outlines stepwise induction protocols. Furthermore, it discusses current applications and prospective developments of cochlea‐on‐a‐chip technologies in areas such as deafness modeling, mechanistic studies, and drug evaluation, with particular focus on gene‐therapy drug
Tian Shen+10 more
wiley +1 more source
Extracellular vesicles adhere to cells primarily by interactions of integrins and GM1 with laminin. [PDF]
Isogai T+11 more
europepmc +1 more source
The cytoplasmic domain of the integrin lymphocyte function-associated antigen 1 beta subunit: sites required for binding to intercellular adhesion molecule 1 and the phorbol ester-stimulated phosphorylation site. [PDF]
Margaret L. Hibbs+4 more
openalex +1 more source
Exosome‐based nanoparticles (GC‐Exo‐CD16Ab) are designed to deliver glucocorticoids (GC) specifically to decidual CD16+ NK cells and macrophages. This targeted delivery effectively suppresses the cytotoxicity of decidual NK cells, inhibits M1 macrophage polarization, and modulates the decidual microenvironment.
Linlin Wang+17 more
wiley +1 more source
Interaction of <i>Serratia proteamaculans</i> with Integrins Activates Invasion-Promoting Signaling Pathways. [PDF]
Tsaplina O.
europepmc +1 more source
The role of protein tyrosine phosphorylation in integrin-mediated gene induction in monocytes. [PDF]
Taichen Lin+6 more
openalex +1 more source