Results 241 to 250 of about 304,001 (345)
Integrin endosomal signalling suppresses anoikis
Jonna Alanko+7 more
semanticscholar +1 more source
This review covers the mechanical forces experienced by immune cells through cell–cell and cell–extracellular matrix interactions and how these forces influence their receptors and functions. These relationships between forces and cellular functions can be exploited using engineering techniques to modify the physical properties of materials for novel ...
Yu‐Chang Chen+2 more
wiley +1 more source
Consolidation of cell-ECM adhesion through direct talin-mediated actin linkage is essential for mouse embryonic morphogenesis. [PDF]
Deng W+6 more
europepmc +1 more source
Emerging microphysiological systems reproduce the spatial, biochemical, and cellular complexity of the tumor microenvironment, surpassing 2D cultures and murine models. By integrating patient‐derived tumors, perfusable vasculature, and immune trafficking, these organ‐on‐chip platforms reveal mechanisms of immune evasion, predict therapeutic responses ...
Fabiana Moresi+5 more
wiley +1 more source
High-grade non-muscle invasive urothelial carcinoma in dogs and humans share specific expression of integrin α5β1. [PDF]
Lucianò R+14 more
europepmc +1 more source
Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar+7 more
wiley +1 more source
FN1 from cancer-associated fibroblasts orchestrates pancreatic cancer metastasis via integrin-PI3K/AKT signaling. [PDF]
Zhu X, Li Y, Liu H, Xiao Z.
europepmc +1 more source