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European Journal of Obstetrics & Gynecology and Reproductive Biology, 1995
Integrins are a large family of cell surface proteins that serve as receptors, involved in cell-cell and cell-matrix interactions. These receptors are of fundamental importance in the organization of tissues and organs. Integrins participate in a complex apparatus anchoring cells to their surrounding and transducing signals into the cells.
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Integrins are a large family of cell surface proteins that serve as receptors, involved in cell-cell and cell-matrix interactions. These receptors are of fundamental importance in the organization of tissues and organs. Integrins participate in a complex apparatus anchoring cells to their surrounding and transducing signals into the cells.
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2014
Integrin α1β1 is widely expressed in mesenchyme and the immune system, as well as a minority of epithelial tissues. Signaling through α1 contributes to the regulation of extracellular matrix composition, in addition to supplying in some tissues a proliferative and survival signal that appears to be unique among the collagen binding integrins.
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Integrin α1β1 is widely expressed in mesenchyme and the immune system, as well as a minority of epithelial tissues. Signaling through α1 contributes to the regulation of extracellular matrix composition, in addition to supplying in some tissues a proliferative and survival signal that appears to be unique among the collagen binding integrins.
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Drug and Therapeutics Bulletin, 1967
Pharmacology - Oxypertine (Integrin-Bayer) has structural affinities with some major phenothiazines, such as trifluoperazine, and also with tryptophan, which has been claimed to elevate mood and increase social contacts in chronic schizophrenics.1 In animals oxypertine is a potent central depressant;2 3 it lowers body temperature ...
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Pharmacology - Oxypertine (Integrin-Bayer) has structural affinities with some major phenothiazines, such as trifluoperazine, and also with tryptophan, which has been claimed to elevate mood and increase social contacts in chronic schizophrenics.1 In animals oxypertine is a potent central depressant;2 3 it lowers body temperature ...
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Integrin activation by talin, kindlin and mechanical forces
Nature Cell Biology, 2019Zhiqi Sun, M. Costell, R. Fässler
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Requirement of vascular integrin alpha v beta 3 for angiogenesis.
Science, 1994Peter C. Brooks, Richard A. F. Clark
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Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
, 1994P. Brooks +6 more
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Integrin-regulated FAK-Src signaling in normal and cancer cells.
Current Opinion in Cell Biology, 2006S. Mitra, D. Schlaepfer
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Neutrophils promote Alzheimer's disease–like pathology and cognitive decline via LFA-1 integrin
Nature Medicine, 2015Elena Zenaro +18 more
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