Results 21 to 30 of about 3,725,063 (205)

Repurposing phenothiazines for cancer therapy: compromising membrane integrity in cancer cells

open access: yesFrontiers in Oncology, 2023
The limitations of current cancer therapies, including the increasing prevalence of multidrug resistance, underscore the urgency for more effective treatments. One promising avenue lies in the repurposing of existing drugs.
Syrina Fred Mehrabi   +3 more
doaj   +1 more source

Grounded Fixpoints and Active Integrity Constraints [PDF]

open access: yes, 2016
The formalism of active integrity constraints was introduced as a way to specify particular classes of integrity constraints over relational databases together with preferences on how to repair existing inconsistencies.
Cruz-Filipe, Luís
core   +3 more sources

Surface modification of flat cable conductors: a path to withstand the aggressive space environment

open access: yesMechanics and Advanced Technologies, 2020
A novel ion-beam surface treatment process with simultaneous surface renewal (IB/SSR) providing charge-dissipative properties to the treated surfaces was developed at ITL and successfully used for treatment of both sides of variously shaped and sized ...
Jacob Kleiman, Zelina Iskanderova
doaj   +1 more source

Sepsis-2.5: Resolving Conflicts Between Payers and Providers

open access: yesCritical Care Explorations, 2023
Competing definitions of sepsis have significant clinical implications and impact both medical coding and hospital payment. Although clinicians may prefer Sepsis-2, payer use of Sepsis-3 to validate clinical diagnoses may result in denial of payment or ...
Howard Rodenberg, MD, MPH   +3 more
doaj   +1 more source

Integrity static analysis of COTS/SOUP [PDF]

open access: yes, 2003
This paper describes the integrity static analysis approach developed to support the justification of commercial off-the-shelf software (COTS) used in a safety-related system.
Bishop, P. G.   +4 more
core   +1 more source

ATAD5 promotes replication restart by regulating RAD51 and PCNA in response to replication stress

open access: yesNature Communications, 2019
How the replisome machinery contributes to fork stability under replication stress is currently not clear. Here the authors reveal a role for ATAD5 in maintaining genome integrity during replication stress by promoting replication restart through RAD51 ...
Su Hyung Park   +14 more
doaj   +1 more source

Proteomic discovery of DEK and NUMA1 as new players in UV-induced DNA damage repair mechanisms

open access: yesCell Death Discovery
Ultraviolet (UV)-induced DNA lesions threaten genomic stability and are associated with skin carcinogenesis. These lesions are primarily repaired by the nucleotide excision repair (NER) pathway.
Namwoo Kim   +7 more
doaj   +1 more source

Longitudinal Observational Study on Quality of Life in Patients with Chronic Wounds Using DLQI and EQ-5D

open access: yesMedicina
Background and Objectives: Chronic wounds severely impair patients’ quality of life (QoL), impacting physical, emotional, and functional well-being.
David Palomar-Albert   +5 more
doaj   +1 more source

Electronic information resources: integration - integration - integration

open access: yesSerials: The Journal for the Serials Community, 2003
This article describes the ELIN@ service (Electronic Library Information Navigator), a system Lund University Libraries have managed to develop to tackle the problem of integration of electronic information resources, increase the use of these resources and make the administration of the e-resources more efficient.The development of the extended ...
Lotte Jørgensen   +4 more
openaire   +1 more source

Convex integration theory without integration [PDF]

open access: yesMathematische Zeitschrift, 2021
We replace the usual Convex Integration formula by a Corrugation Process and introduce the notion of Kuiper differential relations. This notion provides a natural framework for the construction of solutions with self-similarity properties. We consider the case of the totally real relation, we prove that it is Kuiper and we state a totally real ...
openaire   +3 more sources

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