Results 41 to 50 of about 3,730,012 (295)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Radiometric Wireless Sensor Network Monitoring of Partial Discharge Sources in Electrical Substations [PDF]

open access: yes, 2015
A wireless sensor network (WSN) with the potential to monitor and locate partial discharge (PD) in high-voltage electricity substations using only received signal strength (RSS) is proposed.
Jaber, Adel   +28 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Worldwide Integration of Neutron Monitors [PDF]

open access: yesEos, Transactions American Geophysical Union, 2010
Cosmic rays, high‐energy particles that reach Earth's atmosphere from outer space, provide a diagnostic tool to analyze processes of general astrophysical interest, such as the acceleration and transport of highly energetic charged particles in interplanetary space and at the Sun.
openaire   +2 more sources

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Integrity monitoring of Global Navigation Satellite System/Inertial Navigation System integrated navigation system based on dynamic fading filter optimisation

open access: yesIET Radar, Sonar & Navigation, 2022
In the application of integrity monitoring of Global Navigation Satellite System (GNSS)/Inertial Navigation System integrated navigation system in complex environments, such as vegetation covered areas, the Kalman filtering (KF) has the disadvantages of ...
Zhipeng Wang   +4 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Comparative Analysis of Prior and Posterior Integrity Monitoring Techniques for Enhanced Global Navigation Satellite System Positioning Continuity and Accuracy

open access: yesRemote Sensing
GNSS integrity is an essential component for ensuring the reliability of safety-critical applications using Global Navigation Satellite Systems (GNSSs).
Yuting Gao   +4 more
doaj   +1 more source

Minutes: Senate Committee on Student Academic Integrity: March 31, 2021

open access: yes, 2021
In these minutes: Discussion with Executive Vice President and Provost; Debrief on March 16, 2021, Student Panel on Academic Integrity; Discussion on a Proposed MSA Resolution Banning Camera Monitoring Services with Proctoring Software; Acknowledgements ...
University of Minnesota: Senate Committee on Student Academic Integrity
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy