Results 71 to 80 of about 3,730,012 (295)

Design and Performance Evaluation of eLoran Monitoring System

Applied Sciences
The monitoring system is one of the indispensable components of the eLoran system, which can monitor the reliability and integrity of the eLoran system.
Chaozhong Yang, Xiaohang Guo, Shifeng Li, Zhaopeng Hu   +3 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Monitoring File Integrity Using Blockchain and Smart Contracts

IEEE Access, 2020
The adoption of cloud computing solutions is an established reality in government agencies and in small, medium, and large companies due to procurement easiness and the variety of available services, as well as its low cost compared to the acquisition ...
Alexandre Pinheiro, Edna Dias Canedo, Rafael Timoteo De Sousa, Robson De Oliveira Albuquerque   +3 more
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Performance Analysis and Validation of LEO-Augmented SBAS for Global Coverage

Aerospace
All existing Satellite-Based Augmentation Systems (SBAS) are regional, leading to discontinuous global coverage and significant service gaps. To overcome the inherent coverage limitations of SBAS caused by regional ground station distribution, this study
Zhipeng Zhang, Le Wang, Bobin Cui, Ziwei Wang, Guanwen Huang, Haonan She   +5 more
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Multicriteria Collaborative GNSS Integrity Monitoring: Optimization, Spoofing/Jamming Detection, and Performance Evaluation

IEEE Journal of Indoor and Seamless Positioning and Navigation
This study evaluates the performance of a collaborative, multicriteria integrity control method in the presence of Global Navigation Satellite System jamming and spoofing.
Victor Vince, Dominique Heurguier, Alexandre Vervisch Picois, Jose Manuel Rubio Hernan   +3 more
doaj   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Maritime GNSS Threats and Resilience: A Layered Review of Vulnerabilities and Defences

Applied System Innovation
Global Navigation Satellite Systems (GNSS) underpin maritime Positioning, Navigation, and Timing (PNT), supporting bridge functions such as the Automatic Identification System (AIS), the Electronic Chart Display and Information System (ECDIS), radar ...
Dimitrios Piromalis, Efthymios Tserepas, Panagiotis Papageorgas   +2 more
doaj   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

Molecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani, Laura Mariën, Caro De Weerdt, Sanne Wouters, Laure‐Anne Teuwen, Hans Prenen, Katleen Janssens, Timon Vandamme   +7 more
wiley   +1 more source