Results 91 to 100 of about 704,328 (301)
Geoethics: A Challenge for Research Integrity in Geosciences
, 2015 Geoethics reflects the intersection of geology, sociology and philosophy and frequently focuses on important environmental issues and problems often related to natural risk management and mitigation.
Peppoloni, S. +5 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Research Integrity: A Vital Condition for Science & Scholarship
, 2012 Research misconduct is a serious threat to science and to society. A variety of Codes of Conduct for research integrity have been developed in Europe by universities, academies of sciences and funding organisations, but this has resulted in a patchwork ...
Pieter J. D. Drenth
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Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Investigation of Hydraulic and Mechanical Cement Integrity: An Advanced Computational Study [PDF]
, 2021 Cement sheath is a significant barrier to maintain the zonal isolation of wells, preventing severe consequences such as kick (or influx) accidents, environmental contaminations, and safety threats.
Wu, Yuxing
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Risk-based safety analysis of well integrity operations
, 2016 Assurance of well integrity is critical and important in all stages of operation of oil and gas reservoirs. In this study, well integrity is modeled during casing and cementing operations.
Khakzad, N (15574379) +2 more
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Corporate integrity and corporate cash reserves: Insights from textual analysis
International Review of Economics & FinanceWe examine how corporate integrity influences firms’ liquidity policies. Using a large U.S. sample and a text-based measure of corporate integrity developed by Li et al.
Sirimon Treepongkaruna +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Being a trusted and respected partner: The APS integrity framework
, 2019 This paper was commissioned by the Secretariat of the Independent Review of the Australian Public Service (APS) and follows an extensive literature review of leading and international sources, research and analysis of public integrity; consultation ...
Webbe, Simone, Kirby, Nikolas
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