Results 111 to 120 of about 704,328 (301)

Mitigating Integrity Risk in SBAS Positioning Using Enhanced IGG III Robust Estimation

Remote Sensing
To address the limitations in positioning accuracy and the risk of integrity degradation in Satellite-Based Augmentation Systems (SBAS) user-end after applying augmentation information, this study proposes a positioning algorithm integrating an improved ...
Le Wang, Jinbo She, Bobin Cui, Ziwei Wang, Weicong Yang, Yimin Wang   +5 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Well integrity risk assessment in geothermal wells – Status of today

, 2016
In order to map the status of risk assessment methods/techniques and well integrity related to geothermal wells, a literature review and risk assessment survey have been conducted ...
Majoumerd, M.M., Ford, E.P., Randeberg, E., Lohne, H.P.   +3 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Excipient risk analysis: A new ERA? [PDF]

, 2016
Excipient risk management must address the three sources of excipient-related risk; namely, safety, supply chain integrity and technological ...
Brian Carlin
core  

Fault Modes and Methods to Evaluate Integrity Risk for FastSLAM‐Based Navigation

IET Radar, Sonar & Navigation
The fast simultaneous localisation and mapping (FastSLAM), utilising the Rao‐Blackwellised particle filter, provides a robust navigation solution in urban environments.
Pil Hun Choi, Gihun Nam, Dongchan Min, Noah Minchan Kim, Jiyun Lee   +4 more
doaj   +1 more source

Integrating polycyclic aromatic hydrocarbons risk into lake health assessment: A diagnostic framework for ecosystem integrity and services in Dongping Lake, China

Ecological Indicators
Lake ecosystems are vital for sustaining regional ecological security and delivering diverse ecosystem services. However, traditional frameworks often overlook emerging contaminant risks and fail to explicitly link ecological integrity with ecosystem ...
Xinjie Liu, Zengzhe Liu, Xin Li, Jiajing Li, Zhi Dong, Xinchuang Chen, Xiaoqian Li   +6 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Risk based asset integrity indicators

, 2011
Currently, asset integrity is a major concern and presents challenges to the process industry that cannot be ignored. Assessing asset performance is also a difficult task, due to the involvement of versatile tangible, as well as intangible, assets&apos ...
Hassan, MD. Jakiul
core