Results 181 to 190 of about 17,399 (221)
The rise and global spread of IMP carbapenemases (1996-2023): a genomic epidemiology study. [PDF]
Nat CommunVezina B +5 more
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Beyond the Resistome: Molecular Insights, Emerging Therapies, and Environmental Drivers of Antibiotic Resistance. [PDF]
Antibiotics (Basel)Nass NM, Zaher KA.
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Bacterial natural transformation drives cassette shuffling and simplifies recombination in chromosomal integrons. [PDF]
Nucleic Acids ResDebatisse K +7 more
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Mechanisms of antimicrobial resistance: From genetic evolution to clinical manifestations. [PDF]
AIMS MicrobiolNusrat S, Aliyu M, Zohora FT.
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Resistance integrons and super-integrons [PDF]
Clinical Microbiology and Infection, 2004 Integrons are genetic elements composed of a gene encoding an integrase, gene cassettes and an integration site for the gene cassettes (att). The integrase excises and integrates the gene cassettes from and into the integron, but integrons themselves are not mobile. Two groups of integrons are known: resistance integrons and super-integrons. Nearly all
Fluit, A.C., Schmitz, F.-J.
exaly +3 more sources
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Annual Review of Genetics, 2010
Integrons are genetic elements able to acquire and rearrange open reading frames (ORFs) embedded in gene cassette units and convert them to functional genes by ensuring their correct expression. They were originally identified as a mechanism used by Gram-negative bacteria to collect antibiotic resistance genes and express multiple resistance ...
Cambray, Guillaume +2 more
openaire +4 more sources
Integrons are genetic elements able to acquire and rearrange open reading frames (ORFs) embedded in gene cassette units and convert them to functional genes by ensuring their correct expression. They were originally identified as a mechanism used by Gram-negative bacteria to collect antibiotic resistance genes and express multiple resistance ...
Cambray, Guillaume +2 more
openaire +4 more sources
Environmental integrons: the dark side of the integron world
Trends in Microbiology, 2023Integrons are bacterial genetic elements notorious for their role in spreading antibiotic resistance in clinical settings. In the natural environment, integrons present a wide and hidden diversity, raising questions as to their broader role in bacterial adaptation.
Eva Sandoval-Quintana +2 more
openaire +2 more sources
Integrons: Past, Present, and Future [PDF]
Microbiology and Molecular Biology Reviews, 2014 SUMMARY Integrons are versatile gene acquisition systems commonly found in bacterial genomes. They are ancient elements that are a hot spot for genomic complexity, generating phenotypic diversity and shaping adaptive responses. In recent times, they have had a major role in the acquisition, expression, and dissemination of antibiotic ...
Michael R Gillings
exaly +3 more sources
Integrons: agents of bacterial evolution
Nature Reviews Microbiology, 2006Integrons are assembly platforms - DNA elements that acquire open reading frames embedded in exogenous gene cassettes and convert them to functional genes by ensuring their correct expression. They were first identified by virtue of their important role in the spread of antibiotic-resistance genes.
Didier Mazel
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