Biochar and Manure Applications Differentially Altered the Class 1 Integrons, Antimicrobial Resistance, and Gene Cassettes Diversity in Paddy Soils [PDF]
Frontiers in Microbiology, 2022 Integrons are genetic components that are critically involved in bacterial evolution and antimicrobial resistance by assisting in the propagation and expression of gene cassettes.
Niyaz Ali +7 more
doaj +4 more sources
Horizontal transfer and evolution of wall teichoic acid gene cassettes in Bacillus subtilis [version 1; peer review: 1 approved, 2 approved with reservations] [PDF]
F1000Research, 2021 Background: Wall teichoic acid (WTA) genes are essential for production of cell walls in gram-positive bacteria and necessary for survival and variability in the cassette has led to recent antibiotic resistance acquisition in pathogenic bacteria ...
Gary B. Fogel +6 more
doaj +2 more sources
Trade-off between canonical and unusual recombination sites promotes diversity and stability of gene cassette arrays of mobile integrons [PDF]
Scientific ReportsMobile integrons are the most efficient mechanism of Gram-negative bacteria to resist antimicrobial changing pressures in the nosocomial niche. Integron’s integrases mediate site-specific recombination of distinct DNA structures such as attI, attC and ...
Adrián Gonzales Machuca +5 more
doaj +2 more sources
Highly efficient expression of DNA-peptide conjugates in growth-arrested cells [PDF]
Nature CommunicationsEfficient nuclear delivery of DNA remains a major challenge in non-viral gene therapy. While nuclear localization signal (NLS) peptides have been explored for enhancing nuclear translocation of DNA, their efficacy has been limited by DNA-peptide ...
Zulfiqar Y. Mohamedshah +4 more
doaj +2 more sources
The Role of Agriculture in the Dissemination of Class 1 Integrons, Antimicrobial Resistance, and Diversity of Their Gene Cassettes in Southern China [PDF]
Genes, 2020 Niyaz Ali, Dan Xiao, Ahmad Ud Din
exaly +2 more sources
Ecotoxicology and Environmental Safety, 2022 Rapid spread of antibiotic resistance genes (ARGs) in pathogens is threatening human health. Integrons allow bacteria to integrate and express foreign genes, facilitating horizontal transfer of ARGs in environments.
Cai-Xia Zhao +4 more
doaj +1 more source
Frontiers in Environmental Science, 2022 Antimicrobial resistance (AMR) is a serious public health concern. Many countries have implemented AMR surveillance programs for humans and animals, but a scheme for monitoring AMR in the environment has not yet been established. Class 1 integrons, which
Ikuro Kasuga +4 more
doaj +1 more source
Plants, 2022 Transgenic technology can transfer favorable traits regardless of reproductive isolation and is an important method in plant synthetic biology and genetic improvement.
Guannan Qin +8 more
doaj +1 more source
Co-assortment in integron-associated gene cassette assemblages in environmental DNA samples
BMC Genetics, 2010 Background It has been shown that integron-associated gene cassettes exist largely in tandem arrays of variable size, ranging from antibiotic resistance arrays of three to five cassettes up to arrays of more than 100 cassettes associated with the vibrios.
Michael Carolyn A, Andrew Nigel R
doaj +1 more source
Structural diversity of class 1 integrons and their associated gene cassettes in Klebsiella pneumoniae isolates from a hospital in China. [PDF]
PLoS ONE, 2013 BACKGROUND: Klebsiella pneumoniae strains carrying class 1 integrons are becoming more common worldwide, and their role in the dissemination of drug resistance is significant.
Bin Li +7 more
doaj +1 more source