Biochar and Manure Applications Differentially Altered the Class 1 Integrons, Antimicrobial Resistance, and Gene Cassettes Diversity in Paddy Soils [PDF]
Frontiers in Microbiology, 2022 Integrons are genetic components that are critically involved in bacterial evolution and antimicrobial resistance by assisting in the propagation and expression of gene cassettes.
Niyaz Ali +7 more
doaj +4 more sources
Horizontal transfer and evolution of wall teichoic acid gene cassettes in Bacillus subtilis [version 1; peer review: 1 approved, 2 approved with reservations] [PDF]
F1000Research, 2021 Background: Wall teichoic acid (WTA) genes are essential for production of cell walls in gram-positive bacteria and necessary for survival and variability in the cassette has led to recent antibiotic resistance acquisition in pathogenic bacteria ...
Gary B. Fogel +6 more
doaj +2 more sources
The function of integron-associated genes cassettes in Vibrio species: the tip of the iceberg [PDF]
Frontiers in Microbiology, 2013 The integron is a genetic element that incorporates mobile genes termed gene cassettes into a reserved genetic site via site-specific recombination. It is best known for its role in antibiotic resistance with one type of integron, the class 1 integron, a
Rita A Rapa +3 more
doaj +3 more sources
Deletion of integron-associated gene cassettes impact on the surface properties of Vibrio rotiferianus DAT722. [PDF]
PLoS ONE, 2013 BackgroundThe integron is a genetic recombination system that catalyses the acquisition of genes on mobilisable elements called gene cassettes. In Vibrio species, multiple acquired gene cassettes form a cassette array that can comprise 1-3% of the ...
Rita A Rapa +4 more
doaj +3 more sources
A novel cassette method for probe evaluation in the designed biochips. [PDF]
PLoS ONE, 2014 A critical step in biochip design is the selection of probes with identical hybridisation characteristics. In this article we describe a novel method for evaluating DNA hybridisation probes, allowing the fine-tuning of biochips, that uses cassettes with ...
Vitaly Zinkevich +7 more
doaj +17 more sources
Integron gene cassettes: a repository of novel protein folds with distinct interaction sites. [PDF]
PLoS ONE, 2013 Mobile gene cassettes captured within integron arrays encompass a vast and diverse pool of genetic novelty. In most cases, functional annotation of gene cassettes directly recovered by cassette-PCR is obscured by their characteristically high sequence ...
Visaahini Sureshan +8 more
doaj +6 more sources
Trade-off between canonical and unusual recombination sites promotes diversity and stability of gene cassette arrays of mobile integrons [PDF]
Scientific ReportsMobile integrons are the most efficient mechanism of Gram-negative bacteria to resist antimicrobial changing pressures in the nosocomial niche. Integron’s integrases mediate site-specific recombination of distinct DNA structures such as attI, attC and ...
Adrián Gonzales Machuca +5 more
doaj +2 more sources
Highly efficient expression of DNA-peptide conjugates in growth-arrested cells [PDF]
Nature CommunicationsEfficient nuclear delivery of DNA remains a major challenge in non-viral gene therapy. While nuclear localization signal (NLS) peptides have been explored for enhancing nuclear translocation of DNA, their efficacy has been limited by DNA-peptide ...
Zulfiqar Y. Mohamedshah +4 more
doaj +2 more sources
Ecotoxicology and Environmental Safety, 2022 Rapid spread of antibiotic resistance genes (ARGs) in pathogens is threatening human health. Integrons allow bacteria to integrate and express foreign genes, facilitating horizontal transfer of ARGs in environments.
Cai-Xia Zhao +4 more
doaj +1 more source
Frontiers in Environmental Science, 2022 Antimicrobial resistance (AMR) is a serious public health concern. Many countries have implemented AMR surveillance programs for humans and animals, but a scheme for monitoring AMR in the environment has not yet been established. Class 1 integrons, which
Ikuro Kasuga +4 more
doaj +1 more source