The function of integron-associated genes cassettes in Vibrio species: the tip of the iceberg [PDF]
Frontiers in Microbiology, 2013 The integron is a genetic element that incorporates mobile genes termed gene cassettes into a reserved genetic site via site-specific recombination. It is best known for its role in antibiotic resistance with one type of integron, the class 1 integron, a
Rita A Rapa +3 more
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Deletion of integron-associated gene cassettes impact on the surface properties of Vibrio rotiferianus DAT722. [PDF]
PLoS ONE, 2013 BackgroundThe integron is a genetic recombination system that catalyses the acquisition of genes on mobilisable elements called gene cassettes. In Vibrio species, multiple acquired gene cassettes form a cassette array that can comprise 1-3% of the ...
Rita A Rapa +4 more
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Context-driven discovery of gene cassettes in mobile integrons using a computational grammar [PDF]
BMC Bioinformatics, 2009 Background Gene discovery algorithms typically examine sequence data for low level patterns. A novel method to computationally discover higher order DNA structures is presented, using a context sensitive grammar.
Schaeffer Jaron +4 more
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Integron gene cassettes: a repository of novel protein folds with distinct interaction sites. [PDF]
PLoS ONE, 2013 Mobile gene cassettes captured within integron arrays encompass a vast and diverse pool of genetic novelty. In most cases, functional annotation of gene cassettes directly recovered by cassette-PCR is obscured by their characteristically high sequence ...
Visaahini Sureshan +8 more
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Methods for the targeted sequencing and analysis of integrons and their gene cassettes from complex microbial communities. [PDF]
Microb Genom, 2022 Integrons are microbial genetic elements that can integrate mobile gene cassettes. They are mostly known for spreading antibiotic resistance cassettes among human pathogens.
Ghaly TM +6 more
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Impact of Wastewater Treatment on the Prevalence of Integrons and the Genetic Diversity of Integron Gene Cassettes. [PDF]
Appl Environ Microbiol, 2018 The integron platform allows the acquisition, expression, and dissemination of antibiotic resistance genes within gene cassettes. Wastewater treatment plants (WWTPs) contain abundant resistance genes; however, knowledge about the impacts of wastewater ...
An XL +5 more
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Novel broad-host-range vehicles for cloning and shuffling of gene cassettes [PDF]
, 2012 Novel vectors for cloning and shuffling of gene cassettes based on minireplicon of broadhost- range RA3 plasmid from IncU incompatibility group were constructed.
Jolanta Szarlak +9 more
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Kaohsiung Journal of Medical Sciences, 2007 This study characterized class 1 integrons in Escherichia coli in Taiwan. The stability and changes in gene cassettes inserted into integrons were also evaluated. The study included 436 clinical strains of E. coli isolated in 2002. Class 1 integrons were
Lin-Li Chang +2 more
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Integron and its role in antimicrobial resistance: A literature review on some bacterial pathogens [PDF]
Iranian Journal of Basic Medical Sciences, 2021 In recent years, different acquired resistance mechanisms, including transposons, bacteriophages, plasmids, and integrons have been identified as involved in the spread of resistance genes in bacteria.
Parisa Sabbagh +3 more
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Extensions of MADM (mosaic analysis with double markers) in mice. [PDF]
PLoS ONE, 2012 Mosaic Analysis with Double Markers (MADM) is a method for generating genetically mosaic mice, in which sibling mutant and wild-type cells are labeled with different fluorescent markers. It is a powerful tool that enables analysis of gene function at the
Bosiljka Tasic +8 more
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