Results 41 to 50 of about 95,867 (295)

Genomic comparison of diverse Salmonella serovars isolated from swine. [PDF]

, 2019
Food animals act as a reservoir for many foodborne pathogens. Salmonella enterica is one of the leading pathogens that cause food borne illness in a broad host range including animals and humans.
Barrett, John B, Frye, Jonathan G, Gupta, Sushim K, Hiott, Lari M, Humayoun, Shaheen B, Jackson, Charlene R, McClelland, Michael, McMillan, Elizabeth A, Sharma, Poonam, Woodley, Tiffanie   +9 more
core   +2 more sources

Context-driven discovery of gene cassettes in mobile integrons using a computational grammar

BMC Bioinformatics, 2009
Background Gene discovery algorithms typically examine sequence data for low level patterns. A novel method to computationally discover higher order DNA structures is presented, using a context sensitive grammar.
Schaeffer Jaron, Partridge Sally R, Coiera Enrico, Tsafnat Guy, Iredell Jon R   +4 more
doaj   +1 more source

Rescue of splicing-mediated intron loss maximizes expression in lentiviral vectors containing the human ubiquitin C promoter. [PDF]

, 2014
Lentiviral vectors almost universally use heterologous internal promoters to express transgenes. One of the most commonly used promoter fragments is a 1.2-kb sequence from the human ubiquitin C (UBC) gene, encompassing the promoter, some enhancers, first
Cooper, Aaron R, Gschweng, Eric H, Kohn, Donald B, Lill, Georgia R   +3 more
core   +1 more source

Identification and characterization of integron-mediated antibiotic resistance in the phytopathogen Xanthomonas oryzae pv. oryzae. [PDF]

PLoS ONE, 2013
Four streptomycin-resistant isolates of Xanthomonas oryzae pv. oryzae (YNA7-1, YNA10-2, YNA11-2, and YNA12-2) were examined via PCR amplification for the presence of class 1, class 2, and class 3 integrons and aadA1 and aadA2 genes, which confer ...
Ying Xu, Qing-quan Luo, Ming-guo Zhou
doaj   +1 more source

Characterization Integrons and Gene Cassettes in Trimethoprim/Sulfamethoxazole-resistant Stenotrophomonas maltophilia

Journal of Medical Sciences
Background: Integrons in Stenotrophomonas maltophilia are the major mechanism for trimethoprim/sulfamethoxazole (TMP/SMX) resistance. Molecular epidemiology of S.
Jiun-Ji Lai, Yi-Ping Chuang, Rui-Xin Wu, Ching-Mei Yu, Hung-Sheng Shang, Ching-Hsun Wang   +5 more
doaj   +1 more source

Emergence of the mcr-1 colistin resistance gene in extended-spectrum β-lactamase-producing Klebsiella pneumoniae in Taiwan

Journal of Global Antimicrobial Resistance, 2021
Objectives: The resistance ofmcr-1-carrying Enterobacteriaceae to polymyxins, which are last-resort antibiotics, has raised great concern worldwide. In this study, four mcr-1-carrying plasmids isolated from Klebsiella pneumoniae clinical isolates were ...
Yu-Chi Lin, Makoto Kuroda, Satowa Suzuki, Jung-Jung Mu   +3 more
doaj   +1 more source

Cassettes for PCR-mediated gene tagging in Candida albicans utilizing nourseothricin resistance [PDF]

, 2013
addresses: Biosciences, College of Life and Environmental Sciences, University of Exeter, UK.types: Journal Article; Research Support, Non-U.S. Gov't; Validation StudiesThis is the author's post-print version of an article published in Yeast, 2011, Vol ...
Bain, Basso, Bates, Bates, Beckerman, Berman, Brand, Calderone, Cannon, Cheng, Fonzi, Gerami-Nejad, Gerami-Nejad, Gietz, Gillum, Hernday, Lavoie, Linder, Murad, Negredo, Niimi, Noble, Noble, Odds, Perlroth, Reijnst, Reuss, Roemer, Schaub, Shen, Staab, Staab, Wach, Warenda, Wilson, Wilson, Wirsching, Wirsching   +37 more
core   +1 more source

Integrons and Gene Cassettes in the Enterobacteriaceae [PDF]

Antimicrobial Agents and Chemotherapy, 2001
ABSTRACT Integrons were detected in 59 of 120 (49%) urinary isolates of Enterobacteriaceae by PCR using degenerate primers targeted to conserved regions of class 1, 2, and 3 integrase genes. PCR sequencing analysis of the cassette arrays revealed a predominance of cassettes that confer resistance to the ...
White, PA, Mciver, CJ, Rawlinson, WD
openaire   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Inverse correlation between promoter strength and excision activity in class 1 integrons. [PDF]

PLoS Genetics, 2010
Class 1 integrons are widespread genetic elements that allow bacteria to capture and express gene cassettes that are usually promoterless. These integrons play a major role in the dissemination of antibiotic resistance among Gram-negative bacteria.
Thomas Jové, Sandra Da Re, François Denis, Didier Mazel, Marie-Cécile Ploy   +4 more
doaj   +1 more source