Results 51 to 60 of about 3,120,234 (211)
Mobile Gene Cassettes: A fundamental resource for bacterial evolution
, 2008 Horizontal gene transfer increases genetic diversity in prokaryotes to a degree not allowed by the limitations of reproduction by binary fission. The integron/gene cassette system is one of the most recently characterized examples of a system that ...
Andrew, Nigel R +6 more
core +1 more source
Advanced Functional Materials, EarlyView.Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou +6 more
wiley +1 more source
Highly efficient expression of DNA-peptide conjugates in growth-arrested cells
Nature CommunicationsEfficient nuclear delivery of DNA remains a major challenge in non-viral gene therapy. While nuclear localization signal (NLS) peptides have been explored for enhancing nuclear translocation of DNA, their efficacy has been limited by DNA-peptide ...
Zulfiqar Y. Mohamedshah +4 more
doaj +1 more source
A novel cassette method for probe evaluation in the designed biochips. [PDF]
PLoS ONE, 2014 A critical step in biochip design is the selection of probes with identical hybridisation characteristics. In this article we describe a novel method for evaluating DNA hybridisation probes, allowing the fine-tuning of biochips, that uses cassettes with ...
Vitaly Zinkevich +7 more
doaj +1 more source
Measuring Blood Plasma Glutamine Levels Using a Nanopore‐Based Sensor
Advanced Healthcare Materials, EarlyView.Glutamine (GLN) is a biomarker useful for predicting toxic ammonia accumulation. Here, we used a biosensor based on the Cytolysin A (ClyA) nanopore coupled with the GLN‐specific protein substrate‐binding domain 2 (SBD2) to demonstrate real‐time measurement of GLN in blood plasma, highlighting the potential for future point‐of‐care applications ...
Sofia B. Relvas +9 more
wiley +1 more source
New Microbes and New Infections, 2015 A total of 189 Acinetobacter baumannii isolates were collected in 2011 from a teaching hospital in Chongqing, China. Susceptibility data showed strains carrying integrons were significantly more resistant to all tested antibiotics that strains lacking ...
C. Huang +6 more
doaj +1 more source
Antibiotic resistance gene cassettes
The cassette repository was compiled from a previous review (Partridge SR, Tsafnat G, Coiera E et al. Gene cassettes and cassette arrays in mobile resistance integrons.
core +1 more source
Advanced Healthcare Materials, EarlyView.The role of viscoelasticity in the invasion of heterogeneous glioblastoma stem cells (GSCs) was investigated with GSCs categorized into subgroups based on molecular profile, as Reactive, Invasive, or Constructive using viscoelastic biomimetic hyaluronan‐oxime hydrogels.
Nicole J. Blaine +4 more
wiley +1 more source
, 2005 The ease of construction of multiple mutant strains in Schizosaccharomyces pombe is limited by the number of available genetic markers. We describe here three new cassettes for PCR-mediated gene disruption that can be used in combination with commonly ...
Jean Vandenhaute (16066397) +4 more
core +2 more sources
Plants, People, PlanetSocietal Impact Statement Plants and bacteria interact in complex ways that are crucial to the health and productivity of native vegetation and croplands. While the range of characterised plant‐beneficial bacterial traits continues to grow, key questions
Vaheesan Rajabal +7 more
doaj +1 more source