Results 21 to 30 of about 54,378 (282)
Novel Gene Cassettes and Integrons [PDF]
Antimicrobial Agents and Chemotherapy, 2001 ABSTRACT An increase in multiresistant Enterobacteriaceae was observed at one of the departments of the University Medical Center Utrecht. Nine different integrons and 17 gene cassettes were found, including the new gene cassette aadA8 . This cassette was highly related to
E D, Peters +4 more
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Impact of Wastewater Treatment on the Prevalence of Integrons and the Genetic Diversity of Integron Gene Cassettes. [PDF]
Appl Environ Microbiol, 2018 The integron platform allows the acquisition, expression, and dissemination of antibiotic resistance genes within gene cassettes. Wastewater treatment plants (WWTPs) contain abundant resistance genes; however, knowledge about the impacts of wastewater ...
An XL +5 more
europepmc +2 more sources
Tagging genes with cassette-exchange sites [PDF]
Nucleic Acids Research, 2005 In an effort to make transgenesis more flexible and reproducible, we developed a system based on novel 5' and 3' 'gene trap' vectors containing heterospecific Flp recognition target sites and the corresponding 'exchange' vectors allowing the insertion of any DNA sequence of interest into the trapped locus. Flp-recombinase-mediated cassette exchange was
Cobellis G +11 more
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Integrons and Gene Cassettes in the Enterobacteriaceae [PDF]
Antimicrobial Agents and Chemotherapy, 2001 ABSTRACT Integrons were detected in 59 of 120 (49%) urinary isolates of Enterobacteriaceae by PCR using degenerate primers targeted to conserved regions of class 1, 2, and 3 integrase genes. PCR sequencing analysis of the cassette arrays revealed a predominance of cassettes that confer resistance to the ...
White, PA, Mciver, CJ, Rawlinson, WD
openaire +3 more sources
Functional gene cassettes in development. [PDF]
Proceedings of the National Academy of Sciences, 1993 It has been noted in recent years that groups of genes are often used at multiple stages and multiple places of development. Comparison of the functions of each group of genes in different developmental context gave rise to the notion of "functional gene cassettes." These groups of genes can often be viewed as sets of tools; each group is suited to ...
Y N, Jan, L Y, Jan
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Novel broad-host-range vehicles for cloning and shuffling of gene cassettes [PDF]
, 2012 Novel vectors for cloning and shuffling of gene cassettes based on minireplicon of broadhost- range RA3 plasmid from IncU incompatibility group were constructed.
Jolanta Szarlak +9 more
core +1 more source
Kaohsiung Journal of Medical Sciences, 2007 This study characterized class 1 integrons in Escherichia coli in Taiwan. The stability and changes in gene cassettes inserted into integrons were also evaluated. The study included 436 clinical strains of E. coli isolated in 2002. Class 1 integrons were
Lin-Li Chang +2 more
doaj +1 more source
Integron and its role in antimicrobial resistance: A literature review on some bacterial pathogens [PDF]
Iranian Journal of Basic Medical Sciences, 2021 In recent years, different acquired resistance mechanisms, including transposons, bacteriophages, plasmids, and integrons have been identified as involved in the spread of resistance genes in bacteria.
Parisa Sabbagh +3 more
doaj +1 more source
Screening Foodstuffs for Class 1 Integrons and Gene Cassettes. [PDF]
J Vis Exp, 2015 Antibiotic resistance is one of the greatest threats to health in the 21st century. Acquisition of resistance genes via lateral gene transfer is a major factor in the spread of diverse resistance mechanisms. Amongst the DNA elements facilitating lateral transfer, the class 1 integrons have largely been responsible for spreading antibiotic resistance ...
Waldron LS, Gillings MR.
europepmc +4 more sources
Extensions of MADM (mosaic analysis with double markers) in mice. [PDF]
PLoS ONE, 2012 Mosaic Analysis with Double Markers (MADM) is a method for generating genetically mosaic mice, in which sibling mutant and wild-type cells are labeled with different fluorescent markers. It is a powerful tool that enables analysis of gene function at the
Bosiljka Tasic +8 more
doaj +1 more source