Microbial biofilms on macroalgae harbour diverse integron gene cassettes. [PDF]
Microbiology (Reading)Integrons are genetic platforms that capture, rearrange and express mobile modules called gene cassettes. The best characterized gene cassettes encode antibiotic resistance, but the function of most integron gene cassettes remains unknown. Functional predictions suggest that many gene cassettes could encode proteins that facilitate interactions with ...
Freddi S +4 more
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Gene Cassettes Potentially Encoding Fosfomycin Resistance Determinants [PDF]
Antimicrobial Agents and Chemotherapy, 2005 Gene cassettes are small mobile genetic elements that are found in arrays of one or more cassettes within an integron (5, 9). In addition to a single open reading frame, or sometimes two, each cassette contains a unique recombination site that belongs to a family of sites known as 59-be (59-base elements).
Sally R, Partridge, Ruth M, Hall
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Kaohsiung Journal of Medical Sciences, 2007 This study characterized class 1 integrons in Escherichia coli in Taiwan. The stability and changes in gene cassettes inserted into integrons were also evaluated. The study included 436 clinical strains of E. coli isolated in 2002. Class 1 integrons were
Lin-Li Chang +2 more
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Integron and its role in antimicrobial resistance: A literature review on some bacterial pathogens [PDF]
Iranian Journal of Basic Medical Sciences, 2021 In recent years, different acquired resistance mechanisms, including transposons, bacteriophages, plasmids, and integrons have been identified as involved in the spread of resistance genes in bacteria.
Parisa Sabbagh +3 more
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Sequential and counter-selectable cassettes for fission yeast [PDF]
, 2016 BACKGROUND: Fission yeast is one of the most commonly used model organisms for studying genetics. For selection of desirable genotypes, antibiotic resistance cassettes are widely integrated into the genome near genes of interest.
Amelina, H +5 more
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Extensions of MADM (mosaic analysis with double markers) in mice. [PDF]
PLoS ONE, 2012 Mosaic Analysis with Double Markers (MADM) is a method for generating genetically mosaic mice, in which sibling mutant and wild-type cells are labeled with different fluorescent markers. It is a powerful tool that enables analysis of gene function at the
Bosiljka Tasic +8 more
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Spores of Clostridium engineered for clinical efficacy and safety cause regression and cure of tumors in vivo. [PDF]
, 2014 Spores of some species of the strictly anaerobic bacteria Clostridium naturally target and partially lyse the hypoxic cores of tumors, which tend to be refractory to conventional therapies. The anti-tumor effect can be augmented by engineering strains to
Dubois, L +10 more
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Strain prioritization and genome mining for enediyne natural products [PDF]
, 2016 The enediyne family of natural products has had a profound impact on modern chemistry, biology, and medicine, and yet only 11 enediynes have been structurally characterized to date.
Ben Shen +18 more
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Combinatorial Screening for Transgenic Yeasts with High Cellulase Activities in Combination with a Tunable Expression System. [PDF]
PLoS ONE, 2015 Combinatorial screening used together with a broad library of gene expression cassettes is expected to produce a powerful tool for the optimization of the simultaneous expression of multiple enzymes.
Yoichiro Ito +4 more
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A novel expression cassette for the efficient visual selection of transformed tissues in florists' chrysanthemum (Chrysanthemum morifolium Ramat.). [PDF]
, 2011 Constructs carrying visual reporter genes coupled with efficient promoters could facilitate the process of identification and selection of stable transformants in recalcitrant crops.
Jongsma, M.A. +3 more
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