Results 181 to 190 of about 10,885 (211)
Integrons and gene cassettes in clinical isolates of co-trimoxazole-resistant Gram-negative bacteria
Clinical Microbiology and Infection, 2005 Despite a trend of declining consumption, resistance to co-trimoxazole has increased during a 12-year period in Stockholm. The molecular background to this surprising development was investigated by using PCR to screen for integrons and specific ...
Göran Kronvall, L Sundström
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Integron diversity in marine environments
Environmental Science and Pollution Research, 2015Integrons are bacterial genetic elements known to be active vectors of antibiotic resistance among clinical bacteria. They are also found in bacterial communities from natural environments. Although integrons have become especially efficient for bacterial adaptation in the particular context of antibiotic usage, their role in natural environments in ...
Abella, Justine +6 more
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2014
Numerous studies have appeared that describe the importance of resistance integrons (RIs) and superintegrons (SIs) in antibiotic resistance, microbial physiology, and environmental adaptation in phylogenetically diverse gram-negative bacteria. This chapter describes the genetic organization of an integron; summarizes the different classes of RIs and ...
Robert A. Bonomo +2 more
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Numerous studies have appeared that describe the importance of resistance integrons (RIs) and superintegrons (SIs) in antibiotic resistance, microbial physiology, and environmental adaptation in phylogenetically diverse gram-negative bacteria. This chapter describes the genetic organization of an integron; summarizes the different classes of RIs and ...
Robert A. Bonomo +2 more
openaire +1 more source
Molecular Microbiology, 1998
The site‐specific recombinase IntI1, encoded by class 1 integrons, catalyses the integration and excision of gene cassettes by recognizing two classes of sites, the integron‐associated attI1 site and the 59‐base element (59‐be) family of sites that are associated with gene cassettes. IntI1 includes the four conserved amino acids that are characteristic
C M, Collis +3 more
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The site‐specific recombinase IntI1, encoded by class 1 integrons, catalyses the integration and excision of gene cassettes by recognizing two classes of sites, the integron‐associated attI1 site and the 59‐base element (59‐be) family of sites that are associated with gene cassettes. IntI1 includes the four conserved amino acids that are characteristic
C M, Collis +3 more
openaire +2 more sources
On the taxonomy and functions of integrons
2022Integrons are genetic elements that helped precipitate the global antimicrobial resistance crisis. However, the role that integrons have played in the resistance crisis is just a specialised case of their more general role in microbial evolution. Their ability to capture a diverse range of gene cassettes means that they can drive rapid adaptation to ...
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[Structure and function of integrons].
Enfermedades infecciosas y microbiologia clinica, 2002Integrons are genetic elements known for their role in the acquisition and expression of genes conferring antibiotic resistance. Integrons have an integrase gene (intI), an attachment site (attI), into which individual resistance genes are inserted and a promotor sequence (Pant), allowing expression of resistance genes (cassette-associated genes ...
Montserrat, Sabaté, Guillem, Prats
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Transcription of integron‐harboured gene cassette impacts integration efficiency in class 1 integron
Molecular Microbiology, 2011SummaryClass 1 integrons play important roles in the dissemination of antibiotic resistance genes among bacteria. Generally, class 1 integron consists of an integrase gene (intI1), a recombination site (attI1) and a promoter (Pc) that drives the transcription of the downstreamed gene cassettes.
Quhao, Wei +6 more
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Integron and antibiotic resistance
Pathology, 2009Since the advent of antibiotic chemotherapy, the spread of drug resistance genes among clinical isolates of bacteria has become an ever-increasing problem. The increase in drug resistance has been facilitated by the association of antibiotic resistance genes with a variety of mobile genetic elements including plasmids, transposons, integrons and gene ...
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