Results 21 to 30 of about 10,885 (211)
Integrons in the development of antimicrobial resistance: critical review and perspectives
Frontiers in Microbiology, 2023 Antibiotic resistance development and pathogen cross-dissemination are both considered essential risks to human health on a worldwide scale. Antimicrobial resistance genes (AMRs) are acquired, expressed, disseminated, and traded mainly through integrons,
Basharat Ahmad Bhat +6 more
doaj +1 more source
Resistance integrons: class 1, 2 and 3 integrons [PDF]
Annals of Clinical Microbiology and Antimicrobials, 2015 As recently indiscriminate abuse of existing antibiotics in both clinical and veterinary treatment leads to proliferation of antibiotic resistance in microbes and poses a dilemma for the future treatment of such bacterial infection, antimicrobial resistance has been considered to be one of the currently leading concerns in global public health, and ...
Deng, Yang +9 more
openaire +2 more sources
Integrons and integron-related antibiotic resistance in acinetobacter
, 2017 Acinetobacter baumannii is responsible for an increasing number of nosocomial infections in patients receiving intensive care and comprehensive antibiotic resistance of these organisms hampers treatment of infections due to A.baumannii. The molecular basis of antibiotic resistance in A.baumannii has not been extensively investigated. A few studies have
Thomas, Robin
openaire +3 more sources
Microbiome, 2018 Background Integrons, especially the class 1 integrons, are major contributors to the acquisition and dissemination of antibiotic resistance genes (ARGs).
An Ni Zhang +5 more
doaj +1 more source
Into the wild: dissemination of antibiotic resistance determinants via a species recovery program. [PDF]
PLoS ONE, 2013 Management strategies associated with captive breeding of endangered species can establish opportunities for transfer of pathogens and genetic elements between human and animal microbiomes. The class 1 integron is a mobile genetic element associated with
Michelle L Power +2 more
doaj +1 more source
The evolutionary history of chromosomal super-integrons provides an ancestry for multiresistant integrons [PDF]
Proceedings of the National Academy of Sciences, 2001 Integrons are genetic elements that acquire and exchange exogenous DNA, known as gene cassettes, by a site-specific recombination mechanism. Characterized gene cassettes consist of a target recombination sequence ( attC site) usually associated with a single open reading frame coding for an antibiotic resistance
D A, Rowe-Magnus +5 more
openaire +2 more sources
Structural diversity of class 1 integrons and their associated gene cassettes in Klebsiella pneumoniae isolates from a hospital in China. [PDF]
PLoS ONE, 2013 BACKGROUND: Klebsiella pneumoniae strains carrying class 1 integrons are becoming more common worldwide, and their role in the dissemination of drug resistance is significant.
Bin Li +7 more
doaj +1 more source
Mobile Genetic Elements, 2012 Integrons are genetic elements first described at the end of the 1980s. Although most integrons were initially described in human clinical isolates, they have now been identified in many non-clinical environments, such as water and soil. Integrons are present in ≈10% of the sequenced bacterial genomes and are frequently linked to mobile genetic ...
Domingues, Sara +2 more
openaire +2 more sources
Preferential carriage of class 2 integrons in Acinetobacter baumannii CC113 and novel singletons. [PDF]
, 2015 Our understanding of the distribution of integrons associated with multidrug resistance in Acinetobacter baumannii isolates around the world remains incomplete. The association between the class 1 and 2 integron A. baumannii-positive isolates (n = 60),
CENTRÓN, D. +7 more
core +1 more source
Kaohsiung Journal of Medical Sciences, 2007 This study characterized class 1 integrons in Escherichia coli in Taiwan. The stability and changes in gene cassettes inserted into integrons were also evaluated. The study included 436 clinical strains of E. coli isolated in 2002. Class 1 integrons were
Lin-Li Chang +2 more
doaj +1 more source