Results 61 to 70 of about 12,360 (216)
Prevalence of integrons in Aeromonas isolates from fish
National audienceAntimicrobial resistance (AMR) is increasing worldwide in humans, animals and the environment. Integrons are genetic elements involved in the dissemination of AMR, mostly among Gram-negative bacteria.
Le Bouquin-Leneveu, Sophie +12 more
core +2 more sources
Clinical Pseudomonas aeruginosa isolates showed widespread Class 1 and 2 integrons carrying diverse resistance‐associated gene cassettes, including aadB, blaOXA10‐aac(6′)‐II, and aadB‐blaOXA10‐aac(6′)‐Ib, which were strongly associated with antibiotic resistance phenotypes, highlighting the need for enhanced surveillance and targeted infection‐control ...
Mahdi Hosseini Bafghi +2 more
wiley +1 more source
This study integrated genotypic and phenotypic analyses to investigate the persistence of Escherichia coli in treated sewage in Japan. Virulence‐positive isolates were dominated by phylogroups D and B1, with astA and blaTEM as the predominant virulence and resistance determinants. Among accessory siderophore genes, fecA and chuA were the most prevalent.
Ida Munfarida +4 more
wiley +1 more source
Shigellosis is an enteric infectious disease in which antibiotic treatment is effective, shortening the duration of symptoms and reducing the excretion of the pathogen into the environment.
Cecilia S. Toro +12 more
doaj +1 more source
Nasal swabs collected from 400 buffaloes were analysed to determine the prevalence, antimicrobial resistance and virulence characteristics of Staphylococcus aureus and MRSA. MRSA isolates exhibited extensive multidrug resistance and harboured multiple resistance and virulence genes, highlighting their pathogenic and zoonotic potential.
Piash Kumer Ghosh +11 more
wiley +1 more source
The relaxed requirements of the integron cleavage site allow predictable changes in integron target specificity [PDF]
Integrons are able to incorporate exogenous genes embedded in mobile cassettes, by a site-specific recombination mechanism. Gene cassettes are collected at the attI site, via an integrase mediated recombination between the cassette recombination site, attC, and the attI site.
Frumerie, Clara +3 more
openaire +2 more sources
Background Shigella is a frequent cause of bacterial dysentery in the developing world. Treatment with effective antibiotics is recommended for shigellosis, but options become limited due to globally emerging resistance.
Madiyarov Ruslan S +7 more
doaj +1 more source
Background: Escherichia coli strains include both commensal and virulent clones distributed in different phylogenetic groups. Antimicrobial resistance is an increasingly serious public health threat at the global level and integrons are important mobile ...
Yesmi Patricia Ahumada-Santos +6 more
doaj +1 more source
ABSTRACT Systemic antibiotics are effective when used as adjunctive therapy in the treatment of periodontitis; however, their use must be balanced against antimicrobial resistance, which is a major threat to global public health. This review provides an expert synthesis of the literature and a field‐level overview of antimicrobial resistance in ...
Meera Alghafri +3 more
wiley +1 more source
Site-specific deletion and rearrangement of integron insert genes catalyzed by the integron DNA integrase [PDF]
Deletion of individual antibiotic resistance genes found within the variable region of integrons is demonstrated. Evidence for gene duplications and rearrangements resulting from the insertion of gene units at new locations is also presented. Deletion, duplication, and rearrangement occur only in the presence of the integron-encoded DNA integrase ...
C M, Collis, R M, Hall
openaire +2 more sources

