Results 61 to 70 of about 11,919 (172)

Characterization of Integrons and Antimicrobial Resistance in Escherichia coli Sequence Type 131 Isolates

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, 2020
Background. Escherichia coli sequence type 131 (ST131) is an important multidrug-resistant extraintestinal pathogen, which can cause many kinds of infections. Integrons may play a crucial role in the dissemination of antibiotic resistance genes.
Jiangqing Huang   +3 more
doaj   +1 more source

Antarctic soil microbiomes encode structurally conserved and phylogenetically diverse beta‐lactamases

open access: yesiMetaOmics, Volume 3, Issue 3, September 2026.
An integrative metagenomic framework combining sequence, structural, and functional inference reveals a phylogenetically diverse and structurally conserved repertoire of putative beta‐lactamases across Antarctic soil microbiomes, with predominance of class A and subclass B3 enzymes and limited but detectable associations with mobile genetic elements ...
José Coche‐Miranda   +8 more
wiley   +1 more source

Identification of Potential Vaccine Strains of Escherichia coli Isolates From Diarrhoeic Calves

open access: yesVeterinary Medicine and Science, Volume 12, Issue 5, September 2026.
This study aimed to identify vaccine candidate Escherichia coli strains isolated from diarrheic calves. Faecal samples collected from 500 calves were analysed, and E. coli strains were isolated and characterized phenotypically and genotypically. Antibiotic resistance profiles, virulence‐associated genes and MLVA genotyping were used to select 20 ...
Yasemin Erdoğan   +16 more
wiley   +1 more source

Distribution of integrons and phylogenetic groups among highly virulent serotypes of Klebsiella pneumoniae in a Chinese tertiary hospital

open access: yesJournal of Global Antimicrobial Resistance, 2020
Objectives: This study describes the distribution of integrons and phylogenetic groups among clinical highly virulent serotype (HVS) Klebsiella pneumoniae isolates in a Chinese tertiary hospital.
Wenjian Liao   +6 more
doaj   +1 more source

Restoring Meropenem Activity Against VIM‐1‐Producing Klebsiella pneumoniae Through Zinc‐Binding Ligands

open access: yesChemBioChem, Volume 27, Issue 16, 27 August 2026.
Approved zinc‐binding drugs and newly synthesized HisPyr ligands were evaluated as adjuvants to meropenem against metallo‐β‐lactamase‐producing Klebsiella pneumoniae. Chlorpropamide and D‐penicillamine restored meropenem activity against the VIM‐1‐producing strain, while computational analyses supported interactions with the enzyme's binuclear zinc ...
Chiara Ragusa   +6 more
wiley   +1 more source

Dominant Role of Habitat Transformation in Driving the Divergence of Health‐Risk Related Microbial Functional Genes in Karst Mountain Parks: A Metagenomic Study

open access: yesEcology and Evolution, Volume 16, Issue 8, August 2026.
This manuscript elucidates the impact of transforming karst mountain forests into urban parks on health‐risk related microbial functional genes and its implications for mitigating potential public health exposures. Distinctively, the study advances prior research by evaluating the variation in health‐related functional genes within parks of varying ...
Weize Wang, Chunhua Cen, Jingyi Yang
wiley   +1 more source

Integrons: mobilizable platforms that promote genetic diversity in bacteria

open access: yes, 2007
Integrons facilitate the capture of potentially adaptive exogenous genetic material by their host genomes. It is now clear that integrons are not limited to the clinical contexts in which they were originally discovered because ∼10% of bacterial genomes ...
Boucher, Y   +3 more
core   +1 more source

Multidrug-resistant Salmonella enterica serovar Panama carrying class 1 integrons is invasive in Taiwanese children

open access: yesJournal of the Formosan Medical Association, 2013
An increase in group D Salmonella isolates with high antimicrobial resistant rates is being seen in Taiwan. This study aimed to determine the multidrug-resistant (MDR, more than three antibiotics) phenotype, genotype, and the correlation between the ...
Shu-Ching Huang   +3 more
doaj   +1 more source

Antimicrobial Resistance at the Human–Animal–Environment Interface: A One Health Perspective on Drivers, Transmission, and Public Health Responses

open access: yesHealth Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Antimicrobial resistance (AMR) is a global health threat driven by interconnected antimicrobial use and environmental pressures across human, animal, and ecological systems. This review synthesizes current evidence on the major drivers, transmission pathways, reservoirs, surveillance challenges, and public health responses ...
Nurshad Ali
wiley   +1 more source

Integrons and antimicrobial resistance in bacteria: A systematic review [PDF]

open access: yes, 2018
Resistance to antimicrobial agents is on the rise  and this phenomenon not only leads to an increase in economic burden but may also cause serious therapeutic problems.
Goudarzi, Mehdi   +3 more
core   +1 more source

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