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Suffering and Intellectual (Dis)Ability

Cambridge Quarterly of Healthcare Ethics
Abstract This essay argues that what distinguishes a negatively valenced phenomenal experience from suffering is an ability to make meaning of the experience. In this sense, intellectual ability influences the extent and nature of suffering.
openaire   +2 more sources

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Measurement invariance in the assessment of people with an intellectual disability [PDF]

, 2011
Intellectual assessment is central to the process of diagnosing an intellectual disability and the assessment process needs to be valid and reliable. One fundamental aspect of validity is that of measurement invariance, i.e.
MacLean, Hannah, Kidd, Gill, Schwannauer, Matthias, Aja L. Murray, Gill Kidd, Hannah MacLean, Karen McKenzie, Matthias Schwannauer, Murray, Aja Louise, McKenzie, Karen   +9 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

APPARATUS FOR ADDRESSED VIBROMECHANICAL STIMULATION OF INTELLECTUAL ABILITY

Приборы и методы измерений, 2015
The method of addressed vibromechanical stimulation, apparatus for its realization and implementation example has been described. The development is seemed available and effective mean of intellectual ability improvement in responsible and social ...
D. I. Sagaidak, S. V. Shilko, V. V. Yaschuk   +2 more
doaj  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Concurrent validity of the differential ability scales and the Woodcock-Johnson-III Tests of Cognitive Abilities for young children [PDF]

, 2001
Plan BValidation studies assess how comparable intelligence instruments are with regard to the cognitive abilities they assess. Results derived from such studies are used to make inferences as to how instruments are similar and different regarding the ...
Salava, Jennifer Anne
core  

The Effect of the Big Book Media Usage to Simple Sentences’ Reading Ability for Third Grader with Intellectual Disability on Elementary School for Special Needs

Journal of ICSAR, 2017
Child with mild intellectual disability has a resistance of 50-80 IQ intelligence below normal IQ. The purpose of this study is to analyze the effect of the big book media usage towards reading ability of simple sentences for students with mild ...
Putri Karlis Ramadhani, Usep Kustiawan
doaj   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source