Results 101 to 110 of about 4,182,465 (285)
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
International Journal of Gerontology, 2012 Introduction: Higher level functional capacity is considered a crucial component for independent living among the elderly. The aim of the present study was to show the relationships between self-assessed masticatory ability and higher level functional ...
Shingo Moriya +7 more
doaj +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Journal of Intelligence, 2014 Previous research shows that perceived intelligence judgments significantly correlate with measured intelligence scores. The present study investigated the developmental trajectory of the association between perceived intelligence and measured ...
Curtis S. Dunkel, Nora A. Murphy
doaj +1 more source
FEBS Open Bio, EarlyView.Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia +9 more
wiley +1 more source
Melatih Kecerdasan Emosi Anak Usia Dini
INSANIA: Jurnal Pemikiran Alternatif Kependidikan, 2013 : Intelligence should be taught to children as early as possible. The importance of emotional intelligence to teach children to provide better opportunities for them in order to exploit their potential.
Rika Sa’diyah, Rika Sa’diyah
doaj +1 more source
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
The association between contact and Intellectual Disability and Mental Health literacy and stigma [PDF]
, 2014 This thesis examines the association between personal contact with people with intellectual disabilities and schizophrenia and literacy and stigma of the lay public.
Blundell, RC
core
, 2013 Ten young adults with an intellectual disability whose parents, too, have an intellectual disability were interviewed and completed questionnaires for this exploratory study aimed at charting their experiences of everyday life.
Starke, Mikaela,
core +1 more source