Results 31 to 40 of about 282,443 (260)

Ensayos de historia intelectual

open access: yesPerspectivas Metodológicas​, 2023
The title of the dossier alludes to the focus and approach to the object. Essay, first of all, is the most appropriate vocabulary because they are writings that follow the norms of scientific, academic work, but assume that they are first approximations,
Alejandro Herrero
doaj   +2 more sources

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho   +7 more
wiley   +1 more source

Pierre Manent, An Intellectual History of Liberalism

open access: yesJournal of French and Francophone Philosophy, 1997
none
The Editors
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Analytical Concepts for Transcultural Settings: Pathways in Global Intellectual History

open access: yesCromohs: Cyber Review of Modern Historiography
In global intellectual history, there exists a tension between analytical concepts often carrying a Western or colonial pedigree and their ability to capture the multifaceted reality of historical actors who cannot be placed in one language or culture ...
Luc Wodzicki, Sebastian Conrad
doaj   +1 more source

The Episteme and the Historical A Priori: On Foucault’s Archaeological Method

open access: yesJournal of French and Francophone Philosophy, 2021
Interpreters of Michel Foucault's 1966 Les mots et les choses have often conflated the terms 'episteme' and 'historical a priori'. This article suggests that the two terms are entirely separate: while 'episteme' refers to the configuration of thought in ...
Rik Peters
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

L’américanisation d’un intellectuel français : le cas d’Yves Simon (1903-1961)

open access: yesTransatlantica, 2014
In 1938, Yves Simon, who taught philosophy at the Paris and Lille Catholic Institutes, received an invitation to teach at Notre Dame University in Indiana.
Florian Michel
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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