Results 61 to 70 of about 1,561,699 (304)

Utopia and education in the seventeenth century: Bacon’s 'Salomon’s House' and its influence [PDF]

open access: yes, 2010
New Worlds Reflected provides a significant contribution both to the history of utopian literature and travel, and to the wider cultural and intellectual history of the time, assembling original essays from scholars interested in representations of the ...
Houston, Chloe
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

The Post [PDF]

open access: yes, 2005
About the book: Asserting the need for social science historians to examine their own field, this wide-ranging volume offers an intellectual history and critical evaluation of interdisciplinary social science and social science historiography.
Vincent, David
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

(WP 2011-10) Obituary: Warren J. Samuels (1933-2011) [PDF]

open access: yes, 2011
This paper examines the research and career of the late Warren J. Samuels (1933-2011), an influential institutionalist economist in the Wisconsin John Commons tradition and well-known historian and methodologist of economics.
Davis, John
core   +1 more source

Modern International Thought: Problems and Prospects [PDF]

open access: yes, 2014
International intellectual history—the intellectual history of the international and an internationalised intellectual history—has recently emerged as one of the most fertile areas of research in the history of ideas.
Armitage, David R.
core   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Approaches to the History of Philosophical Concepts

open access: yesHistória da Historiografia
This article addresses historiographical questions about the concepts by which philosophy attempts to provide answers to the problems it poses. It argues for a view of philosophy as a historically dynamic intellectual practice that has no clear and ...
Silvia Manzo
doaj   +1 more source

The Powerful

open access: yes, 2004
History is written by the powerful. It is true that since the 1960s and the beginnings of the democratization of history, less powerful minorities have taken up the pen and more profusely expressed their views of history, but to a great extent, white ...
Gale, Molly Kay
core  

The production of ideas: Notes on Austrian intellectual history from Bolzano to Wittgenstein [PDF]

open access: yes, 1981
This paper takes the form of a series of sketches of 19th century Austrian political and intellectual history, allied with a number of more general reflections designed to contribute to our understanding of some of the peculiar characteristics of ...
Smith, Barry
core  

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