Results 51 to 60 of about 1,142,480 (292)

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

The Impact of Intellectual Property Rights Enhancement on Corporate Resilience during Economic Crises

open access: yesJournal of Intellectual Property
This study analyzed the impact of intellectual property rights enhancement on changes in corporate sales and employment and business resilience during economic crises based on ”The Survey of Business Activities” data from 2018 to 2022. The results of the
Minho Kim, Sang-Ok Choi
doaj   +1 more source

A Legal Protection Study of Intellectual Property Rights Infringement Committed by the Artificial Intelligence [PDF]

open access: yesSHS Web of Conferences
The advent of artificial intelligence has led to the development of sophisticated tools and systems that are capable of performing tasks that were previously the exclusive domain of humans.
Bratajaya Maria Magdalena Astrina
doaj   +1 more source

The fundamental right to (intellectual) property and the discretion of the legislature [PDF]

open access: yes, 2013
The article makes two points regarding the fundamental rights dimensions of intellectual property (IP). First, it explains why the prevailing approach to balancing the fundamental right to intellectual property with conflicting fundamental freedoms as if
Peukert, Alexander
core   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Analysis of the relation of copyright and work content in judicial verdicts of USA, UK and Canada

open access: yesMajallah-i ḥuqūq-i taṭbīqī, 2015
According to copyright system, the normal standard for protecting literary and artistic works is originality hence the international copyright treaties such as Berne convention, while emphasizing on originality are avoiding imposing other mandatory ...
Mahmoud Sadeghi, Sara Allameh
doaj  

Penerapan Fungsi Sosial Terhadap Hak Kekayaan Intelektual Di Dalam Masyarakat

open access: yesNagari Law Review, 2019
This article analyzes the position of ideal social functions in IPR which should be regulated by the government. The purpose of writing this article is to examine the social functions of the government to overcome the conflicting intellectual property ...
Chandra Yusuf, Nelly Ulfah Anisariza
doaj   +1 more source

Dasar-Dasar Pemikiran Perlindungan Hak Kekayaan Intelektual

open access: yesProgresif, 2020
Basically, humans are born with different intellectual abilities in processing their thougths and produce somethingfrom that thought. Therefore, it is important to provide protection for the results of thought through the intellectual property rights ...
Darwance Darwance   +2 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

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