Results 51 to 60 of about 9,917,814 (292)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Improving intelligibility and control in Ubicomp [PDF]

open access: yesProceedings of the 12th ACM international conference adjunct papers on Ubiquitous computing - Adjunct, 2010
Users often become frustrated when they are unable to understand and control a ubicomp environment. Previous work has suggested that ubicomp systems should be intelligible to allow users to understand how the system works and controllable to let users intervene when the system makes a mistake.
openaire   +4 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Deciphering spatial domains from spatially resolved transcriptomics through spatially regularized deep graph networks

open access: yesBMC Genomics
Background Recent advancements in spatially resolved transcriptomics (SRT) have opened up unprecedented opportunities to explore gene expression patterns within spatial contexts.
Daoliang Zhang   +7 more
doaj   +1 more source

An Intelligent Gated Fusion Network for Waterbody Recognition in Multispectral Remote Sensing Imagery

open access: yesRemote Sensing
Accurate water body segmentation from multispectral remote sensing imagery is critical for hydrological monitoring and environmental management. However, leveraging transfer learning with pre-trained models remains challenging due to the dimensional ...
Tong Zhao   +3 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Design of a Fano-resonance-enhanced dielectric grating for ultralow-filling-factor superconducting nanowire single-photon detector

open access: yesScientific Reports
Superconducting nanowire single photon detectors (SNSPDs) exhibit excellent performance in the near-infrared band, but their application range is limited by the detection efficiency and detection speed.
Fan Zheng   +7 more
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Intelligent control approach to decentralized routing and flow control in highways

open access: yes, 1997
IEEEProceedings of the 1997 IEEE International Symposium on Intelligent Control -- 16 July 1997 through 18 July 1997 -- Istanbul, Turk -- 47244A decentralized intelligent controller for routing in multi-destination transportation networks is presented ...
İftar, Altuğ
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

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