Results 31 to 40 of about 9,817,156 (285)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Empiricism and Intelligent Design II: Analyzing Intelligent Design [PDF]
, 2011 If intelligent design (ID) is to compete with evolutionary theory (ET), it must meet the modified falsifiability challenge, that is, make some deductive or probabilistic observational assertions.
Lutz, Sebastian
core
Exploring the design applications of key emerging materials from natural sciences through a design ideation workshop [PDF]
, 2023 10th Congress of the International Association of Societies of Design Research (IASDR 2023) 9-13 October 2023, Milan, Italy202405 bcchVersion of ...
Wang, X +15 more
core +1 more source
Nihon Kikai Gakkai ronbunshu, 2018 The number of whiplash injuries worldwide is at a high level. From the mid-1990s, many researchers have focused into the head-neck S-shaped mode deformation behavior in early rear impacts.
Junji HASEGAWA +2 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Low-Power, High Data-Rate Digital Capsule Endoscopy Using Human Body Communication
Applied Sciences, 2018 A technology for low-power high data-rate digital capsule endoscopy with human body communication (CEHBC) is presented in this paper. To transfer the image data stably with low power consumption, the proposed system uses three major schemes: Frequency ...
Mi Jeong Park +6 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Design and Intelligent Machines
AI Magazine, 2017 Many are interested in the design of intelligent machines. I am interested in design and how intelligent machines can transform this human endeavor in positive ways. I would like us to renew our consideration of some of the fundamental questions from the field of artificial intelligence, questions about human creativity and agency, in the context of ...
openaire +3 more sources