Results 21 to 30 of about 31,065 (217)

Testing System Intelligence

open access: yesCoRR, 2023
We discuss the adequacy of tests for intelligent systems and practical problems raised by their implementation. We propose the replacement test as the ability of a system to replace successfully another system performing a task in a given context. We show how it can characterize salient aspects of human intelligence that cannot be taken into account by
openaire   +2 more sources

Health-Related Data Analysis Using Metaheuristic Optimization and Machine Learning

open access: yesIEEE Access
Health-related data has a decisive role in disease diagnosis. Collecting relevant information from health-related data in medical records has been facilitated by evaluating the features of the data.
Annisa Darmawahyuni   +9 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Design and Motion Simulation of a Soft Robot for Crawling in Pipes

open access: yesApplied Bionics and Biomechanics, 2023
In recent years, soft pipeline robot, as a new concept, is proposed to adapt to tunnel. The soft pipeline robots are made of soft materials such as rubber or silicone.
Zhang Yu   +5 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

A systematic review of steel bridge deck pavement in China

open access: yesJournal of Road Engineering, 2023
As an important part of steel bridge deck, the engineering quality and service condition of steel bridge deck pavement (SBDP) directly affects the capacity and operational efficiency of the bridge.
Leilei Chen   +3 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Accurate Detection of Septal Defects With Fetal Ultrasonography Images Using Deep Learning-Based Multiclass Instance Segmentation

open access: yesIEEE Access, 2020
Accurate screening for septal defects is important for supporting radiologists' interpretative work. Some previous studies have proposed semantic segmentation and object detection approaches to carry out fetal heart detection; unfortunately, the models ...
Siti Nurmaini   +7 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

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