Results 31 to 40 of about 17,849,752 (299)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An intelligent recommendation system framework for student relationship management [PDF]
, 2010 In order to enhance student satisfaction, many services have been provided in order to meet student needs. A recommendation system is a significant service which can be used to assist students in several ways.
Philuek, W. +3 more
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Design and Motion Simulation of a Soft Robot for Crawling in Pipes
Applied Bionics and Biomechanics, 2023 In recent years, soft pipeline robot, as a new concept, is proposed to adapt to tunnel. The soft pipeline robots are made of soft materials such as rubber or silicone.
Zhang Yu +5 more
doaj +1 more source
A systematic review of steel bridge deck pavement in China
Journal of Road Engineering, 2023 As an important part of steel bridge deck, the engineering quality and service condition of steel bridge deck pavement (SBDP) directly affects the capacity and operational efficiency of the bridge.
Leilei Chen +3 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
IEEE Access, 2020 Accurate screening for septal defects is important for supporting radiologists' interpretative work. Some previous studies have proposed semantic segmentation and object detection approaches to carry out fetal heart detection; unfortunately, the models ...
Siti Nurmaini +7 more
doaj +1 more source
An Intelligent Decision-Support System for Air Cargo Palletizing [PDF]
, 2021 Palletizing in the air cargo sector faces a large number of constraints (e.g., aviation safety regulations) and represents a highly complex problem. In air cargo operations, there is hardly any digital support to optimize the palletizing process.
Lee, No-San +7 more
core +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Demineralization of cortical bone for improvement of Charpy impact fracture characteristics
Journal of Biomechanical Science and Engineering, 2017 Bone tissue is a composite structure of apatite particles distributed in collagen fibril matrix on a nano-size scale. Mechanical properties of cortical bone are determined by the apatite-collagen composition.
Kazuhiro FUJISAKI +3 more
doaj +1 more source