Results 51 to 60 of about 17,849,752 (299)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

An improved electrocardiogram arrhythmia classification performance with feature optimization

BMC Medical Informatics and Decision Making
Background Automatic classification of arrhythmias based on electrocardiography (ECG) data faces several significant challenges, particularly due to the substantial volume of clinical data involved in ECG signal analysis.
Annisa Darmawahyuni, Siti Nurmaini, Bambang Tutuko, Muhammad Naufal Rachmatullah, Firdaus Firdaus, Ade Iriani Sapitri, Anggun Islami, Jordan Marcelino, Rendy Isdwanta, Muhammad Ikhwan Perwira   +9 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Intelligent Agents - A New Technology for Future Distributed Sensor Systems? [PDF]

, 1999
This master thesis deals with intelligent agents and the possibility to use the intelligent agent technology in future distributed sensor systems.
Andersson, Lisa, Rönnbom, Åsa
core   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Modeling and Vibration Analysis of a 3-UPU Parallel Vibration Isolation Platform with Linear Motors Based on MS-DT-TMM

Shock and Vibration, 2021
The dynamics and vibration characteristics of a 3-UPU parallel mechanism isolator are investigated by theoretical modeling, numerical simulation, and experimental study.
Wei Chen, Jiaqi Tong, Hehe Yang, Fulong Liu, Zhen Qin, Zhiyong Ren   +5 more
doaj   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

AI-assisted diagnosis of cervical dysplasia from cervicography images

Scientific Reports
Cervicography using Visual Inspection with Acetic Acid (VIA) is widely adopted for cervical cancer screening in low-resource settings. Although effective for identifying visible lesions, VIA cannot determine the severity of dysplasia, limiting its ...
Siti Nurmaini, Muhammad Naufal Rachmatullah, Patiyus Agustiansyah, Rizal Sanif, Irawan Sastradinata, Elly Matul Imah, Annisa Darmawahyuni, Bambang Tutuko, Akhiar Wista Arum, Anggun Islami, Firdaus Firdaus, Ade Iriani Sapitri, Aini Nabilah, Radiyati Umi Partan, Rizqi Ayunda Pratama   +14 more
doaj   +1 more source

Computer-aided assessment for enlarged fetal heart with deep learning model

iScience
Summary: Enlarged fetal heart conditions may indicate congenital heart diseases or other complications, making early detection through prenatal ultrasound essential.
Siti Nurmaini, Ade Iriani Sapitri, Muhammad Taufik Roseno, Muhammad Naufal Rachmatullah, Putri Mirani, Nuswil Bernolian, Annisa Darmawahyuni, Bambang Tutuko, Firdaus Firdaus, Anggun Islami, Akhiar Wista Arum, Rio Bastian   +11 more
doaj   +1 more source