Results 91 to 100 of about 159,270 (294)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Dynamics of stratospheric wave reflection over the North Pacific [PDF]

open access: yesWeather and Climate Dynamics
Stratospheric wave reflection events involve the upward propagation of planetary waves, which are subsequently reflected downward by the stratospheric polar vortex.
M. K. Schutte   +5 more
doaj   +1 more source

Observations of an extreme storm in interplanetary space caused by successive coronal mass ejections

open access: yes, 2014
Space weather refers to dynamic conditions on the Sun and in the space environment of the Earth, which are often driven by solar eruptions and their subsequent interplanetary disturbances.
Bale, Stuart D.   +10 more
core   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Submesoscale Vertical Heat Flux Amplifies a Cross‐Scale Positive Feedback in the Western Arabian Sea

open access: yesGeophysical Research Letters
High‐resolution simulations reveal that summer monsoon‐induced upwelling in the western Arabian Sea triggers vigorous submesoscale vertical heat flux (SVHF), challenging the conventional view of winter‐dominant submesoscale activity in open‐ocean ...
Chaoliang Li, Peng Zhan
doaj   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

open access: yesFEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Thermo-Hydraulic Performance of Tubular Heat Exchanger with Opposite-Oriented Trapezoidal Wing Perforated Baffle Plate

open access: yesTehnički Glasnik
A detailed experimental study explored a new axial heat exchanger with swirling air over heated tubes. This heat exchanger features circular baffle plates with perforations and trapezoidal air deflectors at different angles.
Md. Atiqur Rahman   +2 more
doaj   +1 more source

Numerical prediction of the Mid-Atlantic states cyclone of 18-19 February 1979 [PDF]

open access: yes
A series of forecast experiments was conducted to assess the accuracy of the GLAS model, and to determine the importance of large scale dynamical processes and diabatic heating to the cyclogenesis.
Atlas, R., Rosenberg, R.
core   +1 more source

Latent Heat Fluxes over Complex Terrain Measured by Airborne Water Vapour and Wind Lidars [PDF]

open access: yes, 2010
The combination of a water vapour and a wind lidar on an aircraft is an interesting new tool that allows to measure latent heat flux profiles and to portray the small- to mesoscale variability beneath the aircraft trajectory with high accuracy and ...
Kiemle, Christoph
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

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