Results 71 to 80 of about 2,481,320 (272)
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Meteorologische Zeitschrift, 1992 A diagnostic model (acronym DIAMOD) for the free atmosphere is described. Core of DIAMOD is a module which calculates complete thermodynamic budgets of latent and sensible heat, including objective imbalance estimates.
M. Dorninger +4 more
doaj +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
The effect of nonuniform axial heat flux distribution on the critical heat flux [PDF]
, 1965 A systematic experimental and analytic investigation of the effect of nonuniform axial heat flux distribution on critical heat rilux was performed with water in the quality condition.
Todreas, Neil E., Rohsenow, Warren M.
core
Remote SensingThermal infrared (TIR) time series images acquired by ground, proximal TIR stations provide valuable data to study evolution of surface temperature fields of diffuse degassing volcanic areas.
Fabio Sansivero, Giuseppe Vilardo
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Submesoscale Vertical Heat Flux Amplifies a Cross‐Scale Positive Feedback in the Western Arabian Sea
Geophysical Research LettersHigh‐resolution simulations reveal that summer monsoon‐induced upwelling in the western Arabian Sea triggers vigorous submesoscale vertical heat flux (SVHF), challenging the conventional view of winter‐dominant submesoscale activity in open‐ocean ...
Chaoliang Li, Peng Zhan
doaj +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Dynamics of stratospheric wave reflection over the North Pacific [PDF]
Weather and Climate DynamicsStratospheric wave reflection events involve the upward propagation of planetary waves, which are subsequently reflected downward by the stratospheric polar vortex.
M. K. Schutte +5 more
doaj +1 more source