Results 61 to 70 of about 159,995 (298)

Relating extratropical atmospheric heat transport to cyclone life cycle characteristics and numbers in Southern Hemispheric winter [PDF]

open access: yesWeather and Climate Dynamics
Outside the tropics, extratropical cyclones account for most of the poleward atmospheric heat transport, and extreme heat transport events are known to occur in their vicinity.
J. Zibell   +5 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Effects of turbulence structure and urbanization on the heavy haze pollution process [PDF]

open access: yesAtmospheric Chemistry and Physics, 2019
In this paper, an automated algorithm is developed, which is used to identify the spectral gap during the heavy haze pollution process, reconstruct acquired data, and obtain pure turbulence data.
Y. Ren   +5 more
doaj   +1 more source

Anisotropic heating and parallel heat flux in electron-only magnetic reconnection with intense guide fields

open access: yesJournal of Plasma Physics
Electron-only reconnection (E-REC) is a process recently observed in the Earth’s magnetosheath, where magnetic reconnection occurs at electron kinetic scales, and ions do not couple to the reconnection process. Electron-only reconnection is likely to have a significant impact on the energy conversion and dissipation of turbulence cascades at kinetic ...
Jincai Ren   +3 more
openaire   +2 more sources

Latent Heat Fluxes over Complex Terrain from Airborne Water Vapour and Wind Lidars [PDF]

open access: yes, 2009
Tropospheric profiles of water vapour and wind were measured with a differential absorption lidar (DIAL) and a heterodyne detection Doppler wind lidar collo-cated onboard the DLR Falcon research aircraft in the past two years.
Fix, Andreas   +3 more
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

A simple model of the reflection effect for the interacting binaries and extrasolar planets

open access: yes, 2010
Extrasolar planets are a natural extension of the interacting binaries towards the companions with very small masses and similar tools might be used to study them.
Allard   +94 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

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