Results 91 to 100 of about 16,522 (296)

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Intraseasonal response of mixed layer temperature and salinity in the Bay of Bengal to heat and freshwater flux

, 2010
Buoy and satellite data show pronounced subseasonal oscillations of sea surface temperature (SST) in the summertime Bay of Bengal. The SST oscillations are forced mainly by surface heat flux associated with the active break cycle of the south Asian ...
Ravichandran, M, Parampil, SR, Gera, A, Sengupta, D   +3 more
core   +2 more sources

Blue in green: forestation turns blue water green, mitigating heat at the expense of water availability

Environmental Research Letters
In order to meet a stringent carbon budget, shared socioeconomic pathways (SSPs) aligned with the Paris Agreement typically require substantial land-use changes (LUC), such as large-scale forestation and bioenergy crop plantations.
Olivier Asselin, Martin Leduc, Dominique Paquin, Nathalie de Noblet-Ducoudré, Diana Rechid, Ralf Ludwig   +5 more
doaj   +1 more source

Thermo-Hydraulic Performance of Tubular Heat Exchanger with Opposite-Oriented Trapezoidal Wing Perforated Baffle Plate

Tehnički Glasnik
A detailed experimental study explored a new axial heat exchanger with swirling air over heated tubes. This heat exchanger features circular baffle plates with perforations and trapezoidal air deflectors at different angles.
Md. Atiqur Rahman, S. M. Mozammil Hasnain, Rustem Zairov   +2 more
doaj   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Recrystallization, cracking, and erosion of dispersoid-strengthened tungsten materials during exposure to divertor plasmas

Nuclear Materials and Energy
In this study, we investigated the effects of combined intense particle and heat flux exposure on advanced tungsten plasma-facing materials within the DIII-D fusion facility.
R.D. Kolasinski, J.D. Coburn, D.D. Truong, J.G. Watkins, T. Abrams, Z.Z. Fang, R. Hood, R.E. Nygren, A.W. Leonard, J. Ren, D.L. Rudakov, J. Sugar, C. Tsui, H.Q. Wang, J.A. Whaley, I. Bykov, A. Cruz, F. Glass, J. Herfindal, C. Lasnier, C. Marini, A. McLean, A.L. Moser, R. Nishimoto, R. Wilcox, W. York   +25 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Study of Transient Heat Transfer of Melt in Ellipsoidal Lower Head

Yuanzineng kexue jishu
The in-vessel melt retention (IVR) technology, as one of the typical technologies to cope with severe accidents in third-generation nuclear power, is widely used in pressurized water reactor (PWR) nuclear power plants.
LIU Peng1, 2, 3, ZHOU Tao1, 2, 3, LIU Xiaofang1, 2, 3, ZHANG Haolei1, 2, 3, BAI Zongyan1, 2, 3, DUN Shilei1, 2, 3, MAO Shang4
doaj   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source