Results 31 to 40 of about 15,433 (258)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Study of the heat flux fluctuations intensity during flow around a circular cylinder

Journal of Physics: Conference Series, 2021
Abstract An experimental study performed in an air channel using gradient heatmetry is presented, for a configuration of three heated circular cylinders with different distance between them. Cylinders were installed one by one. The main objective is to analyze the heat flux fluctuations, employing gradient heat flux sensor.
V Yu Mityakov, V V Seroshtanov, V V Suchok, N A Zhidkov, A S Vlasov   +4 more
openaire   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Carbon uptake and water use in woodlands and forests in southern Australia during an extreme heat wave event in the “Angry Summer” of 2012/2013 [PDF]

Biogeosciences, 2016
As a result of climate change warmer temperatures are projected through the 21st century and are already increasing above modelled predictions. Apart from increases in the mean, warm/hot temperature extremes are expected to become more prevalent in the ...
E. van Gorsel, S. Wolf, J. Cleverly, P. Isaac, V. Haverd, C. Ewenz, S. Arndt, J. Beringer, V. Resco de Dios, B. J. Evans, A. Griebel, L. B. Hutley, T. Keenan, N. Kljun, C. Macfarlane, W. S. Meyer, I. McHugh, E. Pendall, S. M. Prober, R. Silberstein   +19 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Latent Heat Flux and Turbulent Kinetic Energy Measurements by Lidar in the Frame of the WaLiNeAs Campaign

Remote Sensing
In the present work, we report daytime latent heat flux profile measurements in the convective boundary layer (CBL) obtained from the combined use of a wind lidar and a thermodynamic Raman lidar.
Paolo Di Girolamo, Donato Summa, Ilaria Gandolfi, Marco Di Paolantonio, Marco Rosoldi, Benedetto De Rosa, Davide Dionisi, Cyrille Flamant, Giuseppe D’Amico   +8 more
doaj   +1 more source

The Impact of Baffle Geometry in the PCM Heat Storage Unit on the Charging Process with High and Low Water Streams

Energies, 2022
This paper presents the effect of baffle geometry on the charging process of a low-temperature heat storage unit. Four different geometry variants were considered for this purpose. Each of them was simulated and the results were compared.
Beata Pytlik, Daniel Smykowski, Piotr Szulc   +2 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source