Targeting tumor suppressor gene co-mutations in EGFR-mutant nonsmall cell lung cancer: How ACROSS2 sharpens the case for early intensification. [PDF]
Gunturu KS, Khan H, de Lima Lopes G.
europepmc +1 more source
NKCC1: A key regulator of glioblastoma progression
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Utility of Hybrid Endoscopy Combining Small-Bowel Capsule Endoscopy and Conventional Ileocolonoscopy in Crohn's Disease. [PDF]
Ito T +4 more
europepmc +1 more source
Intensification of Antiretroviral Therapy through Addition of Enfuvirtide in Naive HIV-1-Infected Patients with Severe Immunosuppression Does Not Improve Immunological Response: Results of a Randomized Multicenter Trial (ANRS 130 Apollo) [PDF]
Véronique Joly +12 more
openalex +1 more source
Adding a New Medication Versus Maximizing Dose to Intensify Hypertension Treatment in Older Adults
Carole E. Aubert +5 more
openalex +2 more sources
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Intensified job demands among general practitioners in Finland: associations with work engagement, job satisfaction, and recovery. [PDF]
Öhman O +4 more
europepmc +1 more source
Sustainable intensification: the pathway to low carbon farming? [PDF]
Robert M. Rees +2 more
openalex +1 more source
Optimizing maize–bean cropping systems for sustainable intensification in southern Ethiopia
Tigist Yimer +3 more
openalex +1 more source
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source

