Results 271 to 280 of about 942,007 (409)

Optimizing adjuvant endocrine therapy in premenopausal patients with HER2-positive, hormone receptor-positive breast cancer. [PDF]

Breast
Valenza C, Partridge AH, Regan MM.
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

THE ROLE OF VISUAL AND TECHNICAL MEANS IN THE PROCESS OF INTENSIFICATION OF RUSSIAN AS FOREIGN TEACHING

, 2019
D.D Dmitrieva
openalex   +2 more sources

Incidence of treatment intensification based on HbA1c trends in people with type 2 diabetes. [PDF]

J Diabetes Investig
Sugito E, Sugiyama T, Bouchi R, Tanabe A, Ueki K, Ohsugi M.   +5 more
europepmc   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

A multi-disciplinary effort to provide options for sustainable intensification of African smallholder farming systems

, 2014
Ben A. Lukuyu, Adebayo Abass, Mateete Bekunda   +2 more
openalex   +1 more source

When Clearing Out an Old House Advances Science: The Hump-Shaped Diversity Distribution in Central European Grasslands Better Explained. [PDF]

Glob Chang Biol
Vittoz P.
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Therapeutic Inertia in Lipid-Lowering Treatment: A Narrative Review. [PDF]

J Clin Med
Vatri M, Faggiano A, Angelino E, Ambrosetti M, Faggiano PM, Fattirolli F.   +5 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source