Results 291 to 300 of about 942,007 (409)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

PSMA PET-guided Intensification of Salvage Radiotherapy after Radical Prostatectomy. [PDF]

Radiol Imaging Cancer
Demirci RA, Iravani A.
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Clinical characteristics and intensification patterns in subjects with "early" type 2 diabetes in Italy- an analysis from the AMD annals initiative. [PDF]

Acta Diabetol
Russo GT, Nicolucci A, Cuttone A, Ceriello A, Manicardi V, Rocca A, Prattichizzo F, Lucisano G, Corrao S, De Cosmo S, Di Cianni G, Candido R.   +11 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Efficient Fabrication of Self-Assembled Polylactic Acid Colloidosomes for Pesticide Encapsulation

ACS Omega
Zulipiker Payizila, Fuquan Teng, Xudong Huang, Wenbiao Liu, Tengfei Wu, Qian Sun, Shuangliang Zhao   +6 more
doaj   +1 more source

The beef and veal industry its intensification in the European economic community and South Africa's export possiblities

, 1974
J. Boyazoglu
openalex   +1 more source

Rising atmospheric CO₂ intensifies nitrogen limitation in boreal forests

Kelley R. Bassett
openalex   +1 more source

Reconciling crop production, climate action and nature conservation in Europe by agricultural intensification and extensification. [PDF]

Nat Commun
Hua T, Hu X, Austrheim G, Speed JDM, van Oort B, Cherubini F.   +5 more
europepmc   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source