Results 101 to 110 of about 296,353 (284)

Meteor light curves: the relevant parameters

open access: yes, 2004
We investigate a uniform sample of 113 light curves (LCs) of meteors collected at the Wise Observatory in November 2002 while observing the Leonid meteor shower.
Arlt   +31 more
core   +2 more sources

Parental Death, Shifting Family Dynamics and Female Identity Development [PDF]

open access: yes, 2005
This article is a report of research that explored how the death of a parent influences a woman’s identity development. Qualitative methodology and data analysis procedures based on grounded theory were used for the research.
Cait, Cheryl-Anne
core   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Tuberculosis case finding: evaluation of a paper slip method to trace contacts.

open access: yesPLoS ONE, 2013
SettingSouth Africa has the third highest tuberculosis (TB) burden in the world. Intensified case finding, recommended by WHO, is one way to control TB.ObjectiveTo evaluate the effectiveness and acceptability of a paper slip method for TB contact tracing.
Judith Mwansa-Kambafwile   +5 more
doaj   +1 more source

Guidelines for intensified tuberculosis case-finding and isoniazid preventive therapy for people living with HIV in resource-constrained settings [PDF]

open access: yes
Tuberculosis (TB) is responsible for more than a quarter of deaths in people living with HIV. Isoniazid Preventive Therapy (IPT) and Intensified tuberculosis Case-Finding (ICF) are key public health interventions that significantly reduce the morbidity ...

core  

Place, paradox, and transcendental connection in three of E. M. Forster's novels : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in English at Massey University [PDF]

open access: yes, 2000
E. M. Forster's fiction reflects his own concern with the spirit of place and his seemingly fruitless search for a spiritual reconciliation between people and places.
Flynn, Alice Catherine
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Bilateral invasive lobular breast cancer in a female teenager: a rare finding of a common disease - case report and review of literature [PDF]

open access: yesThe Pan African Medical Journal, 2010
Management of cancer patients in low-resource communities presents enormous challenges. Breast cancer is a public health problem in Cameroon and occurs mostly in elderly women. The predominant histological type is a duct carcinoma.
Ndumbe Peter   +6 more
doaj  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

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